Evidence map›Paper›PMID 25604397›Full record

ArticleScientific reports2015

Fish oil supplements in New Zealand are highly oxidised and do not meet label content of n-3 PUFA.

Benjamin B Albert, José G B Derraik, David Cameron-Smith, Paul L Hofman, Sergey Tumanov, Silas G Villas-Boas, Manohar L Garg, Wayne S Cutfield

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 66 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Microencapsulation of fish oil by spray-drying using two different wall materials: a comparison.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
  16. Article
  17. Review
  18. Do patients benefit from omega-3 fatty acids?Cardiovascular research · 2024
    Review
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Benjamin B AlbertLiggins Institute, University of Auckland, Auckland, New Zealand.
José G B DerraikLiggins Institute, University of Auckland, Auckland, New Zealand.
David Cameron-SmithLiggins Institute, University of Auckland, Auckland, New Zealand.
Paul L HofmanLiggins Institute, University of Auckland, Auckland, New Zealand.
Sergey TumanovCentre for Microbial Innovation, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Silas G Villas-BoasCentre for Microbial Innovation, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Manohar L GargNutraceuticals Research Group, University of Newcastle, Callaghan, New South Wales, Australia.
Wayne S CutfieldLiggins Institute, University of Auckland, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the quality and content of fish oil supplements in New Zealand. All encapsulated fish oil supplements marketed in New Zealand were eligible for inclusion. Fatty acid content was measured by gas chromatography. Peroxide values (PV) and anisidine values (AV) were measured, and total oxidation values (Totox) calculated. Only 3 of 32 fish oil supplements contained quantities of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that were equal or higher than labelled content, with most products tested (69%) containing <67%. The vast majority of supplements exceeded recommended levels of oxidation markers. 83% products exceeded the recommended PV levels, 25% exceeded AV thresholds, and 50% exceeded recommended Totox levels. Only 8% met the international recommendations, not exceeding any of these indices. Almost all fish oil supplements available in the New Zealand market contain concentrations of EPA and DHA considerably lower than claimed by labels. Importantly, the majority of supplements tested exceeded the recommended indices of oxidative markers. Surprisingly, best-before date, cost, country of origin, and exclusivity were all poor markers of supplement quality.

Indexed as

Food AnalysisFood QualityDietary SupplementsDocosahexaenoic AcidsEicosapentaenoic AcidHumansNew ZealandOxidation-ReductionDocosahexaenoic AcidsEicosapentaenoic Acid

Identifiers

PMID25604397
PMCPMC4300506

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.