Evidence map›Paper›PMID 25604184›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2015

Diagnostic contribution of cardiac magnetic resonance in patients with acute coronary syndrome and culprit-free angiograms.

Damian Kawecki, Beata Morawiec, Pierre Monney, Cyril Pellaton, Celina Wojciechowska, Joanna Jojko, Marcin Basiak, Brygida Przywara-Chowaniec, Stephane Fournier, Ewa Nowalany-Kozielska and 2 more

Open access · greenAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Role of cardiovascular magnetic resonance in the prognosis of patients with myocardial infarction with non-obstructive coronary arteries.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  2. Epidemiological Impact of Myocarditis.Journal of clinical medicine · 2021
    Review
  3. Observational
  4. MRI findings in patients with acute coronary syndrome and unobstructed coronary arteries.Diagnostic and interventional radiology (Ankara, Turkey) · 2019
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Impact of extracardiac findings during cardiac MR on patient management and outcome.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Observational
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Damian Kawecki2nd Department of Cardiology, Silesian Medical University, Zabrze, Poland.
Beata Morawiec2nd Department of Cardiology, Silesian Medical University, Zabrze, Poland.
Pierre MonneyCenter of Cardiac Magnetic Resonance, University Hospital, Lausanne, Switzerland.
Cyril PellatonDepartment of Cardiology, University Hospital, Lausanne, Switzerland.
Celina Wojciechowska2nd Department of Cardiology, Silesian Medical University, Zabrze, Poland.
Joanna Jojko2nd Department of Cardiology, Silesian Medical University, Zabrze, Poland.
Marcin BasiakDepartment of Internal Medicine and Clinical Pharmacology, Silesian Medical University, Katowice, Poland.
Brygida Przywara-Chowaniec2nd Department of Cardiology, Silesian Medical University, Zabrze, Poland.
Stephane FournierDepartment of Cardiology, University Hospital, Lausanne, Switzerland.
Ewa Nowalany-Kozielska2nd Department of Cardiology, Silesian Medical University, Zabrze, Poland.
Juerg SchwitterCenter of Cardiac Magnetic Resonance, University Hospital, Lausanne, Switzerland.
Olivier MullerDepartment of Cardiology, University Hospital, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn spite of robust knowledge about underlying ischemic myocardial damage, acute coronary syndromes (ACS) with culprit-free angiograms raise diagnostic concerns. The present study aimed to evaluate the additional value of cardiac magnetic resonance (CMR) over commonly available non-CMR standard tests, for the differentiation of myocardial injury in patients with ACS and non-obstructed coronary arteries. MATERIAL/

methodsPatients with ACS, elevated hs-TnT, and a culprit-free angiogram were prospectively enrolled into the study between January 2009 and July 2013. After initial evaluation with standard tests (ECG, echocardiography, hs-TnT) and provisional exclusion of acute myocardial infarction (AMI) in coronary angiogram, patients were referred for CMR with the suspicion of myocarditis or Takotsubo cardiomyopathy (TTC). According to the result of CMR, patients were reclassified as having myocarditis, AMI, TTC, or non-injured myocardium as assessed by late gadolinium enhancement.

resultsOut of 5110 patients admitted with ACS, 75 had normal coronary angiograms and entered the study; 69 of them (92%) were suspected for myocarditis and 6 (8%) for TTC. After CMR, 49 patients were finally diagnosed with myocarditis (65%), 3 with TTC (4%), 7 with AMI (9%), and 16 (21%) with non-injured myocardium. The provisional diagnosis was changed or excluded in 23 patients (31%), with a 9% rate of unrecognized AMI.

conclusionsThe study results suggest that the evaluation of patients with ACS and culprit-free angiogram should be complemented by a CMR examination, if available, because the initial work-up with non-CMR tests leads to a significant proportion of misdiagnosed AMI.

Indexed as

Acute Coronary SyndromeAdultCardiologyCell DifferentiationCoronary AngiographyCoronary VesselsElectrocardiographyFemaleGadoliniumHumansMagnetic Resonance ImagingMaleMiddle AgedMyocarditisMyocardiumProspective StudiesGadoliniumTroponin

Identifiers

PMID25604184
PMCPMC4345916
OpenAlexW2116632985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.