Evidence map›Paper›PMID 25603796›Full record

ArticleBMB reports2015

Cell type-specific gene expression profiling in brain tissue: comparison between TRAP, LCM and RNA-seq.

TaeHyun Kim, Chae-Seok Lim, Bong-Kiun Kaang

Abstract readComparative Study
In one paragraph

Article in BMB reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

TaeHyun KimDepartment of Biological Sciences, Seoul National University, Seoul 151-747, Korea.
Chae-Seok LimDepartment of Biological Sciences, Seoul National University, Seoul 151-747, Korea.
Bong-Kiun KaangDepartment of Biological Sciences, Seoul National University, Seoul 151-747, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain is an organ that consists of various cell types. As our knowledge of the structure and function of the brain progresses, cell type-specific research is gaining importance. Together with advances in sequencing technology and bioinformatics, cell type-specific transcriptome studies are providing important insights into brain cell function. In this review, we discuss 3 different cell type-specific transcriptome analyses i.e., Laser Capture Microdissection (LCM), Translating Ribosome Affinity Purification (TRAP)/RiboTag, and single cell RNA-Seq, that are widely used in the field of neuroscience.

Indexed as

AnimalsBrainChromatography, AffinityGene Expression ProfilingHumansLaser Capture MicrodissectionOrgan SpecificitySequence Analysis, RNA

Identifiers

PMID25603796
PMCPMC4577288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.