Evidence map›Paper›PMID 25602884›Full record

ArticleAmerican journal of public health2015

Psychotropic drug use among preschool children in the Medicaid program from 36 states.

Lauren D Garfield, Derek S Brown, Benjamin T Allaire, Raven E Ross, Ginger E Nicol, Ramesh Raghavan

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in American journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Use of Antidepressants, Antipsychotics, and Stimulants in Youth Residential Care.Journal of child and adolescent psychopharmacology · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Dosing and Monitoring: Children and Adolescents.Psychopharmacology bulletin · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Patterns of Antipsychotic Prescribing by Physicians to Young Children.Psychiatric services (Washington, D.C.) · 2016
    Article
  16. Somnambulism During Monotherapy With Mixed Amphetamine Salts.Journal of clinical psychopharmacology · 2016
    Article
  17. Article
  18. Review
  19. Off-label Prescribing Trends for ADHD Medications in Very Young Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lauren D GarfieldLauren D. Garfield, Derek S. Brown, Raven E. Ross, Ginger E. Nicol, and Ramesh Raghavan are with Washington University, St Louis, MO. Benjamin T. Allaire is with RTI International, Research Triangle Park, NC.
Derek S Brown
Benjamin T Allaire
Raven E Ross
Ginger E Nicol
Ramesh Raghavan
RTI International · US

Funding

GWB MENTAL HEALTH SERVICE RESEARCH TRAININGT32MH019960 · NIMH · WASHINGTON UNIVERSITY · PI Leopoldo J Cabassa, Byron James Powell · 1995 to 2026
$11.1M
NUTRITION-BEHAVIORAL CARDIOVASCULAR DISEASE PREVENTIONT32HL007456 · NHLBI · WASHINGTON UNIVERSITY · PI WILFLEY, DENISE ELLA · 1985 to 2014
$2.9M
Reducing Disparities in Mental Health Expenditure Among Children in Child WelfareR01MH092312 · NIMH · WASHINGTON UNIVERSITY · PI RAGHAVAN, RAMESH · 2011 to 2013
$797k
STRENGTHENING MEDICAID-FUNDED MENTAL HEALTH COVERAGE FOR CHILDREN IN CHILD WELFARR01HS020269 · AHRQ · WASHINGTON UNIVERSITY · PI RAGHAVAN, RAMESH · 2011 to 2013
$634k
AHRQ HHS R01 HS020269NHLBI NIH HHS 2T32 HL007456-26NHLBI NIH HHS T32 HL007456NIMH NIH HHS R01 MH092312NIMH NIH HHS T32 MH019960PHS HHS HHSN271201200644P
6 · The paper itself

Abstract

objectivesWe determined the prevalence of and indications for psychotropic medication among preschool children in Medicaid.

methodsWe obtained 2000 to 2003 Medicaid Analytic Extract data from 36 states. We followed children in 2 cohorts, born in 1999 and 2000, up to age 4 years. We used logistic regression to model odds of receiving medications for (1) attention-deficit disorder/attention-deficit hyperactivity disorder, (2) depression or anxiety, and (3) psychotic illness or bipolar.

resultsOverall, 1.19% of children received at least 1 psychotropic drug. Medications for attention-deficit disorder/attention-deficit hyperactivity disorder treatment were most common (0.61% of all children), followed by depression or anxiety (0.59%) and psychotic illness or bipolar (0.24%). Among children, boys, those of other or unknown race compared with White, and those with other insurance compared with fee for service-only had higher odds of receiving a prescription (odds ratio [OR]=1.80 [95% confidence interval (CI)=1.74, 1.86], 1.75 [corrected] [1.66, 1.85], and 1.14 [1.01, 1.28], respectively), whereas Black and Hispanic children had lower odds (OR=0.51 [95% CI=0.48, 0.53] and 0.37 [0.34, 0.39], respectively).

conclusionsPreschoolers are receiving psychotropic medications despite limited evidence supporting safety or efficacy. Future research should focus on implementing medication use practice parameters in infant and toddler clinics, and expanding psychosocial interventions for young children with behavioral problems.

Indexed as

Age FactorsAttention Deficit Disorder with HyperactivityBipolar DisorderBrainChild, PreschoolDepressive DisorderDrug UtilizationFemaleHumansInfantInsurance Claim ReviewLogistic ModelsMaleMedicaidOff-Label UsePrescription Drug DiversionPsychotropic Drugs

Identifiers

PMID25602884
PMCPMC4330829
OpenAlexW2126914828

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.