Evidence map›Paper›PMID 25601802›Full record

ArticlePsychiatry research2015

Cognitive control of gaze in bipolar disorder and schizophrenia.

Katharine N Thakkar, Jeffrey D Schall, Gordon D Logan, Sohee Park

Abstract read
In one paragraph

Article in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Attenuated theta-band activity and cross-frequency coupling in schizophrenia during affective response inhibition.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Dissociation of Medial Frontal β-Bursts and Executive Control.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  12. Express saccades during a countermanding task.Journal of neurophysiology · 2020
    Article
  13. Article
  14. Reduced pupil dilation during action preparation in schizophrenia.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2018
    Article
  15. Review
  16. Behavioural and computational varieties of response inhibition in eye movements.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katharine N ThakkarDepartment of Psychology, Vanderbilt University, Nashville, TN, USA; Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands. Electronic address: k.n.thakkar@umcutrecht.nl.
Jeffrey D SchallDepartment of Psychology, Vanderbilt University, Nashville, TN, USA; Center for Integrative Cognitive Neuroscience, Vanderbilt University, Nashville, TN, USA; Vanderbilt Vision Research Center, Vanderbilt University, Nashville, TN, USA.
Gordon D LoganDepartment of Psychology, Vanderbilt University, Nashville, TN, USA; Center for Integrative Cognitive Neuroscience, Vanderbilt University, Nashville, TN, USA; Vanderbilt Vision Research Center, Vanderbilt University, Nashville, TN, USA.
Sohee ParkDepartment of Psychology, Vanderbilt University, Nashville, TN, USA; Center for Integrative Cognitive Neuroscience, Vanderbilt University, Nashville, TN, USA; Department of Psychiatry, Vanderbilt University, Nashville, TN, USA.

Funding

Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
THREE-TIERED PREVENTION MODEL TO BETTER SERVE ALL STUDENP30HD015052 · NICHD · VANDERBILT UNIVERSITY · PI DYKENS, ELISABETH MAY · 1985 to 2014
$18.6M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
NEURAL CONTROL OF VOLUNTARY MOVEMENTR01MH055806 · NIMH · VANDERBILT UNIVERSITY · PI SCHALL, JEFFREY D · 1996 to 2016
$5.2M
Etiology of Working Memory Deficit in SchizophreniaR01MH073028 · NIMH · VANDERBILT UNIVERSITY · PI PARK, SOHEE · 2006 to 2010
$1.4M
Modeling the Role of Priming in Executive ControlR01MH073878 · NIMH · VANDERBILT UNIVERSITY · PI LOGAN, GORDON DENNIS · 2007 to 2009
$725k
Control of action in schizophrenia: Countermanding saccades and ERPF31MH085405 · NIMH · VANDERBILT UNIVERSITY · PI THAKKAR, KATHARINE NATASHA · 2008 to 2011
$78k
NEI NIH HHS P30 EY008126NEI NIH HHS P30-EY08126NICHD NIH HHS P30 HD015052NICHD NIH HHS P30 HD15052NICHD NIH HHS U54 HD083211NIMH NIH HHS F31 MH085405NIMH NIH HHS F31-MH085405-01NIMH NIH HHS MH055806NIMH NIH HHS MH073028NIMH NIH HHS MH073878NIMH NIH HHS R01 MH055806NIMH NIH HHS R01 MH073028NIMH NIH HHS R01 MH073878
6 · The paper itself

Abstract

The objective of the present study was to compare two components of executive functioning, response monitoring and inhibition, in bipolar disorder (BP) and schizophrenia (SZ). The saccadic countermanding task is a translational paradigm optimized for detecting subtle abnormalities in response monitoring and response inhibition. We have previously reported countermanding performance abnormalities in SZ, but the degree to which these impairments are shared by other psychotic disorders is unknown. 18 BP, 17 SZ, and 16 demographically matched healthy controls (HC) participated in a saccadic countermanding task. Performance on the countermanding task is approximated as a race between movement generation and inhibition processes; this model provides an estimate of the time needed to cancel a planned movement. Response monitoring was assessed by the reaction time (RT) adjustments based on trial history. Like SZ patients, BP patients needed more time to cancel a planned movement. The two patient groups had equivalent inhibition efficiency. On trial history-based RT adjustments, however, we found a trend towards exaggerated trial history-based slowing in SZ compared to BP. Findings have implications for understanding the neurobiology of cognitive control, for defining the etiological overlap between schizophrenia and bipolar disorder, and for developing pharmacological treatments of cognitive impairments.

Indexed as

AdultBipolar DisorderExecutive FunctionFemaleHumansInhibition, PsychologicalMalePsychomotor PerformanceSaccadesSchizophreniaCognitive controlCountermandingResponse inhibitionResponse monitoringSaccadesStop signal

Identifiers

PMID25601802
PMCPMC4361560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.