ReviewExpert opinion on drug delivery2015
Carbon nanotubes part I: preparation of a novel and versatile drug-delivery vehicle.
Review in Expert opinion on drug delivery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Biomimetic Carbon-Based Nanomaterials: From Design Strategies to Next-Generation Biosensing and Theranostic Applications.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Regression Modeling of Oxygen-Functionalized Single-Walled Carbon Nanotubes in Aqueous Dispersions.ACS omega · 2025Article
- Therapeutic approach of carbon nanotube: Revolutionize nanomaterial in biomedical and pharmaceutical sector.Journal of food and drug analysis · 2024Review
- Microwave-Assisted Functionalization of Multi-Walled Carbon Nanotubes for Biosensor and Drug Delivery Applications.Pharmaceutics · 2023Review
- Recent Development of Nano-Carbon Material in Pharmaceutical Application: A Review.Molecules (Basel, Switzerland) · 2022Review
- Adsorption of a thione derivative on carbon, AlN, and BN nanotubes: a detailed DFT and MD investigation.Journal of molecular modeling · 2022Article
- Recent Advances in Nano-Formulations for Skin Wound Repair Applications.Drug design, development and therapy · 2022Review
- Functionalized carbon nanotubes: synthesis, properties and applications in water purification, drug delivery, and material and biomedical sciences.Nanoscale advances · 2021Review
- Review
- Carbon Nanotubes: Smart Drug/Gene Delivery Carriers.International journal of nanomedicine · 2021Review
- Light: A Magical Tool for Controlled Drug Delivery.Advanced functional materials · 2020Article
- Genes expression profiling of alveolar macrophages exposed to non-functionalized, anionic and cationic multi-walled carbon nanotubes shows three different mechanisms of toxicity.Journal of nanobiotechnology · 2020Article
- Radiolabeling of amide functionalized multi-walled carbon nanotubes for bioaccumulation study in fish bone using whole-body autoradiography.Environmental science and pollution research international · 2020Article
- Corneal Repair and Regeneration: Current Concepts and Future Directions.Frontiers in bioengineering and biotechnology · 2019Review
- Advances in Carbon Nanotubes for Malignant Melanoma: A Chance for Treatment.Molecular diagnosis & therapy · 2018Review
- Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing.Advanced drug delivery reviews · 2018Review
- Carbon nanotubes in microfluidic lab-on-a-chip technology: current trends and future perspectives.Microfluidics and nanofluidics · 2017Article
- Smart Nanostructures for Cargo Delivery: Uncaging and Activating by Light.Journal of the American Chemical Society · 2017Review
- Effects of lipopolysaccharide, multiwalled carbon nantoubes, and the combination on lung alveolar epithelial cells.Environmental toxicology · 2017Article
- Can We Optimize Arc Discharge and Laser Ablation for Well-Controlled Carbon Nanotube Synthesis?Nanoscale research letters · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
introductionIt is 23 years since carbon allotrope known as carbon nanotubes (CNT) was discovered by Iijima, who described them as "rolled graphite sheets inserted into each other". Since then, CNTs have been studied in nanoelectronic devices. However, CNTs also possess the versatility to act as drug- and gene-delivery vehicles. AREAS COVERED: This review covers the synthesis, purification and functionalization of CNTs. Arc discharge, laser ablation and chemical vapor deposition are the principle synthesis methods. Non-covalent functionalization relies on attachment of biomolecules by coating the CNT with surfactants, synthetic polymers and biopolymers. Covalent functionalization often involves the initial introduction of carboxylic acids or amine groups, diazonium addition, 1,3-dipolar cycloaddition or reductive alkylation. The aim is to produce functional groups to attach the active cargo. EXPERT OPINION: In this review, the feasibility of CNT being used as a drug-delivery vehicle is explored. The molecular composition of CNT is extremely hydrophobic and highly aggregation-prone. Therefore, most of the efforts towards drug delivery has centered on chemical functionalization, which is usually divided in two categories; non-covalent and covalent. The biomedical applications of CNT are growing apace, and new drug-delivery technologies play a major role in these efforts.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.