SynthesisActa ophthalmologica2015
Cataract surgery and age-related macular degeneration. An evidence-based update.
Synthesis in Acta ophthalmologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03944070 (Management of Patients With Neovascular Age-related Macular Degeneration Undergoing Cataract Surgery), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Management of Patients With Neovascular Age-related Macular Degeneration Undergoing Cataract Surgery: A Pilot Study
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Pooled it
- Effect of Phacoemulsification on Visual Acuity and Macular Morphology in Patients with Wet Age-Related Macular Degeneration.Medical science monitor : international medical journal of experimental and clinical research · 2018Trial
- Prevalence of Occult Macular Pathologies Detected by Optical Coherence Tomography in Patients Scheduled for Cataract Surgery.Beyoglu eye journal · 2026Article
- Ocular drug delivery systems based on nanotechnology: a comprehensive review for the treatment of eye diseases.Discover nano · 2025Review
- Cataract surgery decreases risk of falls in elderly patients with comorbid age-related macular degeneration.Clinical & experimental ophthalmology · 2024Article
- Importance of optical coherence tomography before cataract surgery.BMC ophthalmology · 2024Article
- Long Term Visual Outcomes of an Extended Macular Vision IOL in Eyes with Macular Disease and Visually Insignificant Cataract.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Optimising image quality with EyeMax Mono lens in dry age-related macular degeneration.Irish journal of medical science · 2023Article
- Usher Syndrome on the Island of Ireland: A Genotype-Phenotype Review.Investigative ophthalmology & visual science · 2023Article
- Cataract surgery in neovascular AMD: impact on visual acuity and disease activity.BMC ophthalmology · 2023Article
- Eligibility for faricimab in a real-world neovascular age-related macular degeneration population: a cross-sectional study.BMJ open · 2022Article
- Complete Resolution of Central Soft Drusen without Geographic Atrophy or Choroidal Neovascularization.Journal of clinical medicine · 2022Article
- Efficacy of Large Optic Intraocular Lenses in Myopic Eyes with Posterior Segment Pathology.Ophthalmology and therapy · 2022Article
- Association between Cataract Surgery and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis.Journal of ophthalmology · 2022Review
- The Effect of Age-Related Macular Degeneration on Polarization Pattern Perception.Translational vision science & technology · 2021Article
- Predictive Factors for Long-Term Outcomes of Cataract Surgery in Patients Receiving Active Treatment for Neovascular Age-Related Macular Degeneration.Journal of clinical medicine · 2021Article
- Age-Related Macular Degeneration: What Do We Know So Far?Acta medica Lituanic · 2021Review
- Application of evidence-based nursing in patients after cataract surgery and its impacts on visual acuity recovery and psychological status.American journal of translational research · 2021Article
- Effect of cataract surgery on quality of life for patients with severe vision impairment due to age-related macular degeneration.Annals of translational medicine · 2020Article
- Intraocular vision-improving devices in age-related macular degeneration.Annals of translational medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAge-related macular degeneration (AMD) and cataract often coexist in patients and concerns that cataract surgery is associated with an increased risk of incidence or progression of existing AMD has been raised. This systematic review and meta-analysis is focused on presenting the evidence concerning progression of AMD in patients undergoing cataract surgery.
methodsWe performed a systematic literature search in the PubMed, Medline, Cochrane Library and CINAHL databases. Two randomized trials and two case-control trials were identified. Quality of the studies was assessed using the Cochrane risk of bias tool, data were extracted, and meta-analyses were performed. Quality of the available evidence was evaluated using the GRADE system.
resultsWe found that visual acuity at 6-12 months follow-up was significantly better (6.5-7.5 letters) in eyes that had undergone cataract surgery than in unoperated eyes, but the included number of subjects was small, and hence, the quality of evidence was downgraded to moderate. We did not find an increased risk of progression to exudative AMD 6-12 months after cataract surgery [RR 3.21 (0.14-75.68)], but the included number of subjects was small, and thus, the quality of the evidence was moderate.
conclusionCataract surgery increases visual acuity without an increased risk of progression to exudative AMD, but further research with longer follow-up is encouraged.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.