SynthesisBJOG : an international journal of obstetrics and gynaecology2015
When is birthweight at term (≥37 weeks' gestation) abnormally low? A systematic review and meta-analysis of the prognostic and predictive ability of current birthweight standards for childhood and adult outcomes.
Synthesis in BJOG : an international journal of obstetrics and gynaecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of size at birth on health, growth and developmental outcomes in children up to age 18: an umbrella review.Archives of disease in childhood · 2023Pooled it
- Association between size at birth, rapid weight gain in infancy, and overweight status among Palestinian refugees under 5 years old: a retrospective cohort study.The American journal of clinical nutrition · 2026Article
- Clinical Opinion: The diagnosis and management of suspected fetal growth restriction: an evidence-based approach.American journal of obstetrics and gynecology · 2022Review
- Term Birth Weight and Neurodevelopmental Outcomes.Epidemiology (Cambridge, Mass.) · 2021Article
- Modeling the impact of exposure reductions using multi-stressor epidemiology, exposure models, and synthetic microdata: an application to birthweight in two environmental justice communities.Journal of exposure science & environmental epidemiology · 2021Article
- Transcriptome-wide analysis of changes in the fetal placenta associated with prenatal arsenic exposure in the New Hampshire Birth Cohort Study.Environmental health : a global access science source · 2019Article
- Article
- Nonhuman primate breath volatile organic compounds associate with developmental programming and cardio-metabolic status.Journal of breath research · 2018Article
- Prevalence of diabetes and obesity in association with prematurity and growth restriction.Diabetes, metabolic syndrome and obesity : targets and therapy · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundHealth outcomes throughout the life course have been linked to fetal growth restriction and low birthweight. A variety of measures exist to define low birthweight, with a lack of consensus regarding which predict adverse outcome.
objectivesTo evaluate the relationship between birthweight standards and childhood and adult outcomes in term-born infants (≥37 weeks' gestation). SEARCH STRATEGY: MEDLINE (1966-January 2011), EMBASE (1980-January 2011), and the Cochrane Library (2011:1) and MEDION were included. SELECTION CRITERIA: Studies comprising live term-born infants (gestation ≥37 completed weeks), with weight or other anthropometric measurements recorded at birth along with childhood and adult outcomes. DATA COLLECTION AND ANALYSIS: Data were extracted to populate 2 × 2 tables relating birthweight standard with outcome, and meta-analysis was performed where possible. MAIN
resultsFifty-nine articles (2 600 383 individuals) were selected. There was no significant relationship between birthweight <2.5 kg (odds ratio [OR] 0.98, 95% confidence intervals [CI] 0.87-1.10) and composite measure of childhood morbidity. Weight <10th centile on the population nomogram showed a small association (OR 1.49, 95% CI 1.02-2.19) for the same outcome. There was no significant association between either of the above measures and adult morbidity. The relationship between other measures and individual outcomes varied. AUTHOR'S
conclusionsThe association between low birthweight, by any definition, and childhood and adult morbidity was inconsistent. None of the current standards of low birthweight was a good predictor of adverse outcome.
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