ArticleMolecular systems biology2015
Linked circadian outputs control elongation growth and flowering in response to photoperiod and temperature.
Article in Molecular systems biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed.
- Photoperiod-dependent regulation of secondary growth by auxin flux: how it occurs and how to benefit from it.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Stable and dynamic gene expression patterns over diurnal and developmental timescales in Arabidopsis thaliana.The New phytologist · 2025Article
- Abundant clock proteins point to missing molecular regulation in the plant circadian clock.Molecular systems biology · 2025Article
- Rhizosphere microbiomes of field-grownFrontiers in microbiology · 2025Article
- Forward genetic approach identifies a phylogenetically conserved serine residue critical for the catalytic activity of UBIQUITIN-SPECIFIC PROTEASE 12 in Arabidopsis.Scientific reports · 2024Article
- Decoding the plant clock: a review of mathematical models for the circadian regulatory network.Plant molecular biology · 2024Review
- Exploring the interplay between angiosperm chlorophyll metabolism and environmental factors.Planta · 2024Review
- Circadian and photoperiodic regulation of the vegetative to reproductive transition in plants.Communications biology · 2024Review
- Core clock genes adjust growth cessation time to day-night switches in poplar.Nature communications · 2024Article
- Phosphorylation mediated regulation of RNA splicing in plants.Frontiers in plant science · 2023Review
- Genome-Wide Identification and Analysis ofGenes · 2022Article
- COP1 dynamics integrate conflicting seasonal light and thermal cues in the control ofScience advances · 2022Article
- Rising rates of starch degradation during daytime and trehalose 6-phosphate optimize carbon availability.Plant physiology · 2022Article
- The circadian clock mutant lhy cca1 elf3 paces starch mobilization to dawn despite severely disrupted circadian clock function.Plant physiology · 2022Article
- A spatial model of the plant circadian clock reveals design principles for coordinated timing.Molecular systems biology · 2022Article
- Modelling of plant circadian clock for characterizing hypocotyl growth under different light quality conditions.In silico plants · 2022Article
- Article
- PHYTOCHROME INTERACTING FACTORS PIF4 and PIF5 promote heat stress induced leaf senescence in Arabidopsis.Journal of experimental botany · 2021Article
- A framework of artificial light management for optimal plant development for smart greenhouse application.PloS one · 2021Article
- Transcriptomic Analysis of Changes in Gene Expression During Flowering Induction in Sugarcane Under Controlled Photoperiodic Conditions.Frontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Clock-regulated pathways coordinate the response of many developmental processes to changes in photoperiod and temperature. We model two of the best-understood clock output pathways in Arabidopsis, which control key regulators of flowering and elongation growth. In flowering, the model predicted regulatory links from the clock to cycling DOF factor 1 (CDF1) and flavin-binding, KELCH repeat, F-box 1 (FKF1) transcription. Physical interaction data support these links, which create threefold feed-forward motifs from two clock components to the floral regulator FT. In hypocotyl growth, the model described clock-regulated transcription of phytochrome-interacting factor 4 and 5 (PIF4, PIF5), interacting with post-translational regulation of PIF proteins by phytochrome B (phyB) and other light-activated pathways. The model predicted bimodal and end-of-day PIF activity profiles that are observed across hundreds of PIF-regulated target genes. In the response to temperature, warmth-enhanced PIF4 activity explained the observed hypocotyl growth dynamics but additional, temperature-dependent regulators were implicated in the flowering response. Integrating these two pathways with the clock model highlights the molecular mechanisms that coordinate plant development across changing conditions.
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