Evidence map›Paper›PMID 25600291›Full record

ArticleBiological psychology2015

Resting-state EEG delta power is associated with psychological pain in adults with a history of depression.

Esther L Meerwijk, Judith M Ford, Sandra J Weiss

Abstract read
In one paragraph

Article in Biological psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Review
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  7. Article
  8. EEG connectivity features associated with fibromyalgia revealed by machine learning.Frontiers in pain research (Lausanne, Switzerland) · 2025
    Article
  9. Article
  10. Relation between heart rate variability and spectral analysis of electroencephalogram in chronic neuropathic pain patients.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. The Link between Suicidality and Electroencephalography Asymmetry: A Systematic Review and Meta-analysis.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023
    Review
  15. Article
  16. Review
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  19. Changes in Brain Electrical Activity According to Post-traumatic Stress Symptoms in Survivors of the Sewol Ferry Disaster: A 1-year Longitudinal Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Esther L MeerwijkDepartment of Community Health Systems, University of California, San Francisco, 2 Koret Way No. N505, San Francisco, CA 94143-0606, USA. Electronic address: esther.meerwijk@ucsf.edu.
Judith M FordSan Francisco VA Medical Center, San Francisco, CA, USA; Department of Psychiatry, University of California, San Francisco, CA, USA.
Sandra J WeissDepartment of Community Health Systems, University of California, San Francisco, 2 Koret Way No. N505, San Francisco, CA 94143-0606, USA.

Funding

NURSING RESEARCH TRAINING IN SYMPTOM MANAGEMENTT32NR007088 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, KATHRYN · 1996 to 2015
$7.5M
Rescuing the ruminating brain: Identifying biomarkers of rumination and mindfulness through concurrent EEG and fMRI studies of schizophrenia and depressionI01CX000497 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI Judith M Ford · 2011 to 2026
–
CSRD VA I01 CX000497NINR NIH HHS T32 NR007088
6 · The paper itself

Abstract

Psychological pain is a prominent symptom of clinical depression. We asked if frontal alpha asymmetry, frontal EEG power, and frontal fractal dimension asymmetry predicted psychological pain in adults with a history of depression. Resting-state frontal EEG (F3/F4) was recorded while participants (N=35) sat upright with their eyes closed. Frontal delta power predicted psychological pain while controlling for depressive symptoms, with participants who exhibited less power experiencing greater psychological pain. Frontal fractal dimension asymmetry, a nonlinear measure of complexity, also predicted psychological pain, such that greater left than right complexity was associated with greater psychological pain. Frontal alpha asymmetry did not contribute unique variance to any regression model of psychological pain. As resting-state delta power is associated with the brain's default mode network, results suggest that the default mode network was less activated during high psychological pain. Findings are consistent with a state of arousal associated with psychological pain.

Indexed as

AdultArousalBrainDepressionDepressive DisorderElectroencephalographyFemaleHumansMaleMiddle AgedPainYoung AdultDefault mode networkDepressionEEGMental painNonlinear measuresPsychological pain

Identifiers

PMID25600291
PMCPMC4336814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.