Evidence map›Paper›PMID 25600080›Full record

ArticleJournal of feline medicine and surgery2015

Haematological and biochemical reference intervals in adult Maine Coon cat blood donors.

Eva Spada, Maria Teresa Antognoni, Daniela Proverbio, Elisabetta Ferro, Vittorio Mangili, Arianna Miglio

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Wild Felids Blood Group System.Animals : an open access journal from MDPI · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eva SpadaVeterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Milan, Italy eva.spada@unimi.it.
Maria Teresa AntognoniVeterinary Transfusion Unit (EMOVET-UNIPG), Department of Veterinary Clinical Science, University of Perugia, Perugia, Italy.
Daniela ProverbioVeterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Milan, Italy.
Elisabetta FerroVeterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Milan, Italy.
Vittorio MangiliVeterinary Transfusion Unit (EMOVET-UNIPG), Department of Veterinary Clinical Science, University of Perugia, Perugia, Italy.
Arianna MiglioVeterinary Transfusion Unit (EMOVET-UNIPG), Department of Veterinary Clinical Science, University of Perugia, Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objectives of this study were to derive Maine Coon haematological and biochemical reference intervals (RIs) from adult healthy blood donors, to validate (or reject) the use of published RIs for the general feline population in this breed, and to evaluate the effects of age, sex and weight on the haematological and biochemical results.

methodsHaematological and biochemical data were retrieved retrospectively from a database of 81 healthy adult Maine Coon cat blood donors and were analysed to generate normal RIs. RIs were determined and compared with established non-breed-specific feline RIs according to the Clinical and Laboratory Standards Institute guidelines and the American Society of Veterinary Clinical Pathology guidelines using Reference Value-Advisor (version 2.1) software.

resultsThe age of the cats ranged from 1-8 years (mean 4.4 years), 42 were female and 39 were male, and weights ranged from 4.9-8.5 kg (mean 6.7 kg). New Maine Coon RIs were proposed for red blood cell count, mean corpuscular volume, mean corpuscular haemoglobin concentration, reticulocyte count and percentage. Haematocrit was higher in male cats (mean HCT 42.9% vs 41% in females; P = 0.001) and in heavier cats (P = 0.003; slope 1.0, regression equation HCT = 35.1 + 1.0 × weight). New biochemical RIs were proposed for urea, aspartate aminotransferase, γ-glutamyl transpeptidase (GGT), alkaline phosphatase, total protein and albumin in Maine Coons. Females had higher GGT (median GGT value in females 4.0 vs 3.0 in males; P = 0.011) and albumin values (mean albumin value 3.3 in females vs 3.1 in males; P = 0.013). CONCLUSIONS AND RELEVANCE: Currently published RIs for some haematological and biochemical parameters are not appropriate for use in adult Maine Coon cats. A breed-specific variation could be a plausible explanation for the new haematological and serum biochemical analytes proposed in this study. Breed-specific RIs for Maine Coon cats will help prevent misinterpretation of laboratory results in diagnosis and in the selection of ideal blood donors.

Indexed as

Blood DonorsBreedingAlanine TransaminaseAlkaline PhosphataseAnimalsBlood Cell CountBody WeightCatsFemaleHematocritMaleReference ValuesAlanine TransaminaseAlkaline Phosphatase

Identifiers

PMID25600080
PMCPMC10816339

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.