ArticleDigestive diseases and sciences2015
Prevalence of esophageal eosinophilia and eosinophilic esophagitis in adults: a population-based endoscopic study in Shanghai, China.
Article in Digestive diseases and sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Meta-Analysis: Inverse Association Between Helicobacter pylori Infection and Eosinophilic Oesophagitis.Alimentary pharmacology & therapeutics · 2025Pooled it
- Association Between Helicobacter pylori Exposure and Decreased Odds of Eosinophilic Esophagitis-A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019Pooled it
- Meta-Analysis-Based Guidance for Dietary Management in Eosinophilic Esophagitis.Current gastroenterology reports · 2015Pooled it
- Differences in adult eosinophilic esophagitis between Japan and Western countries.Journal of gastroenterology · 2026Review
- Long-term course of untreated asymptomatic esophageal eosinophilia and minimally symptomatic eosinophilic esophagitis.Endoscopy international open · 2024Article
- Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe.Current allergy and asthma reports · 2024Review
- Eosinophilic gastrointestinal disorders: a narrative review on clinical perspectives and research gaps in the Asian context.Translational gastroenterology and hepatology · 2024Review
- Eosinophilic esophagitis in children: A cross-sectional study from a tertiary care center.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Eosinophilic esophagitis-established facts and new horizons.Seminars in immunopathology · 2021Review
- How to approach adult patients with asymptomatic esophageal eosinophilia.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2021Review
- Risk of progression to eosinophilic esophagitis in patients with asymptomatic esophageal eosinophilia: A retrospective pilot study.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Regional Differences in Food Allergies.Clinical reviews in allergy & immunology · 2019Review
- Obesity and hiatal hernia may be non-allergic risk factors for esophageal eosinophilia in Japanese adults.Esophagus : official journal of the Japan Esophageal Society · 2019Article
- Association between endoscopic findings of eosinophilic esophagitis and responsiveness to proton pump inhibitors.Endoscopy international open · 2019Article
- Epidemiology and Natural History of Eosinophilic Esophagitis.Gastroenterology · 2018Review
- Diagnosis and treatment of eosinophilic esophagitis in clinical practice.Clinical journal of gastroenterology · 2017Review
- Eosinophilic Esophagitis From an Allergy Perspective: How to Optimally Pursue Allergy Testing & Dietary Modification in the Adult Population.Current gastroenterology reports · 2016Review
- Food allergy and eosinophilic esophagitis in India: Lack of diagnosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2016Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimPopulation-based endoscopic studies of esophageal eosinophilia and eosinophilic esophagitis are limited in the world. This study was aiming to describe features of esophageal eosinophilia and eosinophilic esophagitis in a representative sample of the adult in Shanghai, China.
methodsAs part of a large epidemiological study, 3,600 individuals (aged 18-80 years) were randomly selected in Shanghai, China. They were asked to undergo endoscopy and have at least four esophageal biopsies taken from 0.5 cm above the Z-line and any abnormal areas. Any eosinophil infiltration of the epithelium was defined as esophageal eosinophilia. Eosinophilic esophagitis was defined as ≥15 eosinophils/high-power field in esophageal biopsies.
resultsA total of 1,030 individuals accepted to have endoscopy and 1,021 individuals with biopsy results were suitable for analysis. Esophageal eosinophilia was present in 67 subjects (6.6 %). Eosinophilic esophagitis was present in four cases (0.4 %). No significant association was found between the presence of esophageal eosinophilia and reflux esophagitis, Barrett's esophagus, symptom-defined gastroesophageal reflux disease or H. pylori infection. Most individuals with esophageal eosinophilia (80.6 %) did not have any of the upper gastrointestinal symptoms.
conclusionsEsophageal eosinophilia was present in nearly 6.6 % of the general adult population of China; 0.4 % had eosinophilic esophagitis. Most of individuals with esophageal eosinophilia were asymptomatic.
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