Evidence map›Paper›PMID 25599559›Full record

ArticleNutrition & diabetes2015

Impact of vitamin D supplementation on adiposity in African-Americans.

P D Chandler, J B Scott, B F Drake, K Ng, A T Chan, B W Hollis, K M Emmons, E L Giovannucci, C S Fuchs, G G Bennett

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition & diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

P D Chandler1] Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA [2] Harvard Medical School, Boston, MA, USA.
J B ScottDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
B F DrakeDepartment of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO, USA.
K Ng1] Harvard Medical School, Boston, MA, USA [2] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
A T Chan1] Harvard Medical School, Boston, MA, USA [2] Department of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.
B W HollisDivision of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.
K M Emmons1] Harvard Medical School, Boston, MA, USA [2] Center for Community-Based Research, Dana-Farber Cancer Institute, Boston, MA, USA.
E L Giovannucci1] Harvard Medical School, Boston, MA, USA [2] Department of Nutrition, Harvard School of Public Health, Boston, MA, USA [3] Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
C S Fuchs1] Harvard Medical School, Boston, MA, USA [2] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
G G BennettDepartment of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Harvard University · USBrigham and Women's Hospital · USDana-Farber Cancer Institute · USDuke University · USMedical University of South Carolina · USMichigan State University · USWashington University in St. Louis · US

Funding

Tissue and Pathology ResourcesP50CA127003 · NCI · DANA-FARBER CANCER INST · PI SHIVDASANI, RAMESH A · 2007 to 2023
$33.2M
VITamin D and omegA-3 triaL (VITAL)U01CA138962 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., MANSON, JOANN ELISABETH · 2009 to 2014
$23.6M
Impact of Celecoxib and Inflammation on Survival in Stage III Colon CancerR01CA169141 · NCI · YALE UNIVERSITY · PI FUCHS, CHARLES S · 2013 to 2018
$3.9M
Role of Vitamin D, Inflammation, and Energy Balance in Colorectal Cancer SurvivalK07CA148894 · NCI · DANA-FARBER CANCER INST · PI NG, KIMMIE · 2011 to 2015
$889k
Dissemination Research to Reduce Cancer DisparitiesK05CA124415 · NCI · DANA-FARBER CANCER INST · PI EMMONS, KAREN M. · 2007 to 2011
$810k
Community-based Obesity Prevention among BlacksK22CA126992 · NCI · DUKE UNIVERSITY · PI BENNETT, GARY G · 2007 to 2009
$529k
NCI NIH HHS K05 CA124415NCI NIH HHS K07 CA148894NCI NIH HHS K22 CA126992NCI NIH HHS P50 CA127003NCI NIH HHS R01 CA169141NCI NIH HHS U01 CA138962
6 · The paper itself

Abstract

backgroundAfrican-Americans have higher rates of obesity-associated chronic diseases. Serum 25-hydroxyvitamin D (25(OH)D) shows an inverse association with obesity status. We investigated whether vitamin D supplementation changes body mass index (BMI). SUBJECTS: In total, 328 overweight African-Americans were enrolled over three consecutive winter periods (2007-2010) into a randomized, double-blind, placebo-controlled trial to receive cholecalciferol supplementation (0, 1000 international units (IU), 2000 IU or 4000 IU per day) for 3 months. Plasma concentrations of 25(OH)D and anthropometric measurements were done at baseline, 3 and 6 months.

resultsAt 3 months, vitamin D supplementation in three dose groups (1000 IU, 2000 IU or 4000 IU per day) did not cause any significant changes in BMI as compared with placebo group 3-month change in BMI per 1000 IU per day estimate (SE): 0.01 (0.039); P=0.78.

conclusionsIn overweight African-Americans, short-term high-dose vitamin D supplementation did not alter BMI.

Identifiers

PMID25599559
PMCPMC4314577
OpenAlexW2125886664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.