Evidence map›Paper›PMID 25599324›Full record

ArticleAnnals of surgery2015

Total pancreatectomy with islet autotransplantation: summary of an NIDDK workshop.

Melena D Bellin, Andres Gelrud, Guillermo Arreaza-Rubin, Ty B Dunn, Abhinav Humar, Katherine A Morgan, Bashoo Naziruddin, Cristiana Rastellini, Michael R Rickels, Sarah J Schwarzenberg and 1 more

Abstract readConference Proceedings
In one paragraph

Article in Annals of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Academic Pancreas Centers of Excellence: Guidance from a multidisciplinary chronic pancreatitis working group at PancreasFest.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
    Guideline
  3. Review
  4. Observational
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Pre-operative Sarcopenia Predicts Low Islet Cell Yield Following Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Article
  19. Article
  20. Pancreatic Cysts in the Elderly.Current treatment options in gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Melena D Bellin*Departments of Pediatrics and Surgery, University of Minnesota Medical School, Minneapolis, MN †Department of Medicine, Pritzker School of Medicine, Center for Endoscopic Research and Therapeutics (CERT), Chicago, IL ‡Division of Diabetes, Endocrinology, and Metabolism and Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD §Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA ¶Department of Surgery, Medical University of South Carolina, Charleston, SC ‖Baylor Simmons Transplant Institute, Dallas, TX **Department of Surgery, University of Texas Medical Branch, Galveston, TX; and ††Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Andres Gelrud
Guillermo Arreaza-Rubin
Ty B Dunn
Abhinav Humar
Katherine A Morgan
Bashoo Naziruddin
Cristiana Rastellini
Michael R Rickels
Sarah J Schwarzenberg
Dana K Andersen

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Institutional Career Development CoreKL2TR002492 · NCATS · UNIVERSITY OF MINNESOTA · PI INGBAR, DAVID H · 2018 to 2022
$6.3M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)KL2TR000113 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$5.4M
Sitagliptin therapy to improve outcomes after islet autotransplantation.K23DK084315 · NIDDK · UNIVERSITY OF MINNESOTA · PI BELLIN, MELENA D. · 2010 to 2014
$816k
NCATS NIH HHS KL2 TR000113NCATS NIH HHS UL1 TR000114NIDDK NIH HHS K23 DK084315
6 · The paper itself

Abstract

A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases focused on research gaps and opportunities in total pancreatectomy with islet autotransplantation (TPIAT) for the management of chronic pancreatitis. The session was held on July 23, 2014 and structured into 5 sessions: (1) patient selection, indications, and timing; (2) technical aspects of TPIAT; (3) improving success of islet autotransplantation; (4) improving outcomes after total pancreatectomy; and (5) registry considerations for TPIAT. The current state of knowledge was reviewed; knowledge gaps and research needs were specifically highlighted. Common themes included the need to identify which patients best benefit from and when to intervene with TPIAT, current limitations of the surgical procedure, diabetes remission and the potential for improvement, opportunities to better address pain remission, GI complications in this population, and unique features of children with chronic pancreatitis considered for TPIAT. The need for a multicenter patient registry that specifically addresses the complexities of chronic pancreatitis and total pancreatectomy outcomes and postsurgical diabetes outcomes was repeatedly emphasized.

Indexed as

Islets of Langerhans TransplantationPancreatectomyBiomedical ResearchChronic PainGuidelines as TopicHumansPancreatitis, ChronicPatient SelectionRegistriesTime FactorsTransplantation, AutologousTransplantation, HomologousTreatment OutcomeUnited StatesUnited States Food and Drug Administration

Identifiers

PMID25599324
PMCPMC4567980

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.