ArticleNature neuroscience2015
The development of cortical circuits for motion discrimination.
Article in Nature neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed.
- Noise-invariant representations of sound emerge along the canonical cortical hierarchy.PLoS biology · 2026Article
- Early Development of Direction Selectivity in the Higher Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Connectivity, Computation, and Plasticity of the Early Visual System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Functional architecture for speed tuning in primary visual cortex of carnivores.bioRxiv : the preprint server for biology · 2025Article
- Stereotyped Spatiotemporal Dynamics of Spontaneous Activity in Visual Cortex Prior to Eye Opening.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Developmental maturation of millimeter-scale functional networks across brain areas.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Network state transitions during cortical development.Nature reviews. Neuroscience · 2024Review
- Developmental maturation of millimeter-scale functional networks across brain areas.bioRxiv : the preprint server for biology · 2024Article
- Hormone-mediated neural remodeling orchestrates parenting onset during pregnancy.Science (New York, N.Y.) · 2023Article
- Roles of visually evoked and spontaneous activity in the development of retinal direction selectivity maps.Trends in neurosciences · 2022Review
- Internally generated population activity in cortical networks hinders information transmission.Science advances · 2022Article
- Balanced Enhancements of Synaptic Excitation and Inhibition Underlie Developmental Maturation of Receptive Fields in the Mouse Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Article
- Synaptic and intrinsic mechanisms underlying development of cortical direction selectivity.eLife · 2020Article
- An early phase of instructive plasticity before the typical onset of sensory experience.Nature communications · 2020Article
- Article
- Stimulus complexity shapes response correlations in primary visual cortex.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Distributed network interactions and their emergence in developing neocortex.Nature neuroscience · 2018Article
- Thalamus Controls Development and Expression of Arousal States in Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Thalamocortical function in developing sensory circuits.Current opinion in neurobiology · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Stimulus discrimination depends on the selectivity and variability of neural responses, as well as the size and correlation structure of the responsive population. For direction discrimination in visual cortex, only the selectivity of neurons has been well characterized across development. Here we show in ferrets that at eye opening, the cortical response to visual stimulation exhibits several immaturities, including a high density of active neurons that display prominent wave-like activity, a high degree of variability and strong noise correlations. Over the next three weeks, the population response becomes increasingly sparse, wave-like activity disappears, and variability and noise correlations are markedly reduced. Similar changes were observed in identified neuronal populations imaged repeatedly over days. Furthermore, experience with a moving stimulus was capable of driving a reduction in noise correlations over a matter of hours. These changes in variability and correlation contribute significantly to a marked improvement in direction discriminability over development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.