ArticleJournal of clinical & translational endocrinology2014
Vitamin D Status, Receptor Gene Polymorphisms, and Supplementation on Tuberculosis: A Systematic Review of Case-Control Studies and Randomized Controlled Trials.
Article in Journal of clinical & translational endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Association of vitamin D receptor genetic variants with therapeutic response in multidrug-resistant pulmonary tuberculosis: a systematic review.Frontiers in cellular and infection microbiology · 2026Pooled it
- Vitamin D and the risk of latent tuberculosis infection: a systematic review and meta-analysis.BMC pulmonary medicine · 2022Pooled it
- Effectiveness of vitamin D supplementation on the outcome of pulmonary tuberculosis treatment in adults: a meta-analysis of randomized controlled trials.Chinese medical journal · 2019Pooled it
- Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysis.PLoS medicine · 2019Pooled it
- Prevalence of vitamin D deficiency and the effect of vitamin D3 supplementation on response to anti-tuberculosis therapy in patients with extrapulmonary tuberculosis.BMC infectious diseases · 2024Trial
- Vitamin D Receptor Gene FokI Polymorphism in Patient with Human Immunodeficiency Virus - Tuberculosis Coinfection and Associated Risk Factors.Infection & chemotherapy · 2025Article
- Protective Role of Vitamin D Against Development of Active Tuberculosis in Close Household Contacts of Pulmonary Tuberculosis Patients: A Prospective Cohort Study.Indian journal of clinical biochemistry : IJCB · 2024Article
- Serum Vitamin D Levels in Pediatric Tuberculosis Patients in a Tertiary Care Center in India: A Case-Control Study.Cureus · 2023Article
- Association of Single-Nucleotide Polymorphisms in theInfection and drug resistance · 2023Article
- Preparation and Evaluation of Low-Dose Calcitriol Dry Powder Inhalation as Host-Directed Adjunct Therapy for Tuberculosis.Pharmaceutical research · 2022Article
- VDR gene polymorphisms are associated with the increased susceptibility to COVID-19 among iranian population: A case-control study.International journal of immunogenetics · 2022Article
- Tuberculosis conundrum - current and future scenarios: A proposed comprehensive approach combining laboratory, imaging, and computing advances.World journal of radiology · 2022Review
- The Progress of the Prevention and Treatment of Vitamin D to Tuberculosis.Frontiers in nutrition · 2022Review
- Type 2 Diabetes Mellitus and Altered Immune System Leading to Susceptibility to Pathogens, EspeciallyJournal of clinical medicine · 2019Review
- Mycobacterium tuberculosis and macrophage nuclear receptors: What we do and don't know.Tuberculosis (Edinburgh, Scotland) · 2019Review
- Macrophage nuclear receptors: Emerging key players in infectious diseases.PLoS pathogens · 2019Review
- 25-Hydroxyvitamin D concentrations in dogs with naturally acquired blastomycosis.Journal of veterinary internal medicine · 2018Article
- Vitamin D supplementation as a control program against latent tuberculosis infection in Korean high school students.Epidemiology and health · 2018Article
- Vitamin D status of tuberculosis patients with diabetes mellitus in different economic areas and associated factors in China.PloS one · 2018Article
- Factors influencing the higher incidence of tuberculosis among migrants and ethnic minorities in the UK.F1000Research · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the impacts of vitamin D status, supplementation and vitamin D receptor (VDR) gene polymorphisms on tuberculosis (TB).
methodsWe conducted a systematic review of published studies pertaining to case-control and randomized-control trials from 2002 to 2014 using the PubMed database. RESULTS AND
conclusionIndividuals with TB have lower vitamin D status than healthy individuals. Some VDR gene polymorphisms are associated with increased susceptibility to TB while others may not. Supplementation with vitamin D leads to improved clinical outcomes. However, further studies with a larger patient population and different ethnicities are needed to confirm these effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.