ArticleKorean journal of radiology
Rapid increase in marrow fat content and decrease in marrow perfusion in lumbar vertebra following bilateral oophorectomy: an MR imaging-based prospective longitudinal study.
Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Factors Predisposing to The Formation of Degenerative Spondylolisthesis-A Narrative Review.Medicina (Kaunas, Lithuania) · 2023Review
- The Relationship Between Bone Mineral Density and Lumbar Disc Herniation in Postmenopausal Women.Cureus · 2023Article
- Advances in Bone Marrow Imaging: Strengths and Limitations from a Clinical Perspective.Seminars in musculoskeletal radiology · 2023Article
- Clinical correlation between osteoporotic thoracolumbar vertebral compression fractures and lumbar spondylolisthesis.International orthopaedics · 2022Article
- Article
- Percentage fat fraction in magnetic resonance imaging: upgrading the osteoporosis-detecting parameter.BMC medical imaging · 2020Article
- A study of dynamic contrast-enhanced MR imaging features and influence factors of pelvic bone marrow in adult females.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Marrow adipose tissue imaging in humans.Bone · 2019Review
- Senile osteoporosis is associated with disc degeneration.Quantitative imaging in medicine and surgery · 2018Article
- Comparison of semi-quantitative and quantitative dynamic contrast-enhanced MRI evaluations of vertebral marrow perfusion in a rat osteoporosis model.BMC musculoskeletal disorders · 2017Article
- Lumbar degenerative spondylolisthesis epidemiology: A systematic review with a focus on gender-specific and age-specific prevalence.Journal of orthopaedic translation · 2017Review
- Postmenopausal Chinese women show accelerated lumbar disc degeneration compared with Chinese men.Journal of orthopaedic translation · 2015Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
objectiveBilateral oophorectomy leads to reduced bone mineral density (BMD), and reduced BMD is associated with increased marrow fat and reduced marrow perfusion. Purpose of this study was to investigate how soon these changes occur following surgical oophorectomy. MATERIALS AND
methodsSix patients who underwent hysterectomy and bilateral salpingo-oophorectomy were studied. At baseline, mean patient age was 49.5 years (range: 45-54 years). Third lumbar vertebral body BMD measurement using quantitative CT, marrow fat fraction (FF) using MR spectroscopy and marrow perfusion using dynamic contrast enhanced MRI were conducted immediately prior to surgery and at 3, 9, and 21 months after surgery.
resultsReduced BMD, increased marrow FF, and reduced marrow perfusion occurred synchronously post-oophorectomy. There was a sharp decrease of 12.5 ± 7.2% in BMD (n = 6), a sharp increase of 92.2 ± 46.3% (n = 6) in FF, a sharp decrease of 23.6 ± 3.9% in maximum contrast enhancement (n = 5), and of 45.4 ± 7.7% for enhancement slope (n = 5) during the initial 3 months post surgery. BMD and marrow perfusion continued to decrease, and marrow FF continued to increase at a slower rate during the following 18 months. Friedman test showed a significant trend for these changes (p < 0.05).
conclusionBilateral oophorectomy leads to a rapid decrease in lumbar BMD, an increase in marrow fat content, and a decrease in marrow blood perfusion.
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