Evidence map›Paper›PMID 25598563›Full record

ArticleTrends in analytical chemistry : TRAC2015

Emerging trends in optical sensing of glycemic markers for diabetes monitoring.

Rishikesh Pandey, Narahara Chari Dingari, Nicolas Spegazzini, Ramachandra R Dasari, Gary L Horowitz, Ishan Barman

Open access · greenAbstract read
In one paragraph

Article in Trends in analytical chemistry : TRAC, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Advanced mid-infrared lightsources above and beyond lasers and their analytical utility.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2022
    Review
  5. Serum Glycated Albumin Levels Are Affected by Alcohol in Men of the Jinuo Ethnic Group in China.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rishikesh PandeyLaser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.
Narahara Chari DingariLaser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.
Nicolas SpegazziniLaser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.
Ramachandra R DasariLaser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.
Gary L HorowitzDivision of Clinical Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, 02215, USA.
Ishan BarmanDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.
Massachusetts Institute of Technology · USBeth Israel Deaconess Medical Center · USJohns Hopkins Medicine · US

Funding

Wide-Field Short-Wave Infrared (SWIR) multiphoton (MP) tissue imagingP41EB015871 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2012 to 2021
$11.3M
NIBIB NIH HHS P41 EB015871
6 · The paper itself

Abstract

In the past decade, considerable attention has been focused on the measurement of glycemic markers, such as glycated hemoglobin and glycated albumin, that provide retrospective indices of average glucose levels in the bloodstream. While these biomarkers have been regularly used to monitor long-term glucose control in established diabetics, they have also gained traction in diabetic screening. Detection of such glycemic markers is challenging, especially in a point-of-care setting, due to the stringent requirements for sensitivity and robustness. A number of non-separation based measurement strategies were recently proposed, including photonic tools that are well suited to reagent-free marker quantitation. Here, we critically review these methods while focusing on vibrational spectroscopic methods, which offer highly specific molecular fingerprinting capability. We examine the underlying principles and the utility of these approaches as reagentless assays capable of multiplexed detection of glycemic markers and also the challenges in their eventual use in the clinic.

Indexed as

DiabetesDiabetes monitoringFructosamineGlycemic markerHbA1cOptical sensingPhotonicsPoint of careRaman scatteringSpectroscopy

Identifiers

PMID25598563
PMCPMC4295656
OpenAlexW2018987083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.