Evidence map›Paper›PMID 25598118›Full record

ArticleJournal of pediatric surgery2015

Does timing of neonatal inguinal hernia repair affect outcomes?

Jason P Sulkowski, Jennifer N Cooper, Eileen M Duggan, Ozlem Balci, Seema P Anandalwar, Martin L Blakely, Kurt Heiss, Shawn Rangel, Peter C Minneci, Katherine J Deans

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of pediatric surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Risk of incarceration in children with inguinal hernia: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2019
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  12. Delaying surgery for inguinal hernia in neonates: Is it worthwhile?Journal of Taibah University Medical Sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jason P SulkowskiCenter for Surgical Outcomes Research, Department of Surgery and the Research Institute, Nationwide Children's Hospital, Columbus, OH.
Jennifer N CooperCenter for Surgical Outcomes Research, Department of Surgery and the Research Institute, Nationwide Children's Hospital, Columbus, OH.
Eileen M DugganDepartment of Pediatric Surgery, Monroe Carell Jr Children's Hospital, Nashville, TN.
Ozlem BalciDepartment of Pediatric Surgery, Children's Hospital of Atlanta, Atlanta, GA.
Seema P AnandalwarDepartment of Pediatric Surgery, Children's Hospital Boston, Boston, MA.
Martin L BlakelyDepartment of Pediatric Surgery, Monroe Carell Jr Children's Hospital, Nashville, TN.
Kurt HeissDepartment of Pediatric Surgery, Children's Hospital of Atlanta, Atlanta, GA.
Shawn RangelDepartment of Pediatric Surgery, Children's Hospital Boston, Boston, MA.
Peter C MinneciCenter for Surgical Outcomes Research, Department of Surgery and the Research Institute, Nationwide Children's Hospital, Columbus, OH.
Katherine J DeansCenter for Surgical Outcomes Research, Department of Surgery and the Research Institute, Nationwide Children's Hospital, Columbus, OH. Electronic address: katherine.deans@nationwidechildrens.org.
Nationwide Children's Hospital · USBoston Children's Museum · USChildren's Healthcare of Atlanta · USMonroe Carell Jr. Children's Hospital · US

Funding

Training in Congenital and Acquired Heart DiseaseT32HL098039 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI GARG, VIDU, MOHLER, PETER J. · 2009 to 2019
$2.5M
NHLBI NIH HHS T32 HL098039
6 · The paper itself

Abstract

purposeThe purpose of this study was to examine practice variability and compare outcomes between early and delayed neonatal inguinal hernia repair (IHR).

methodsPatients admitted to neonatal intensive care units with a diagnosis of IH who underwent IHR by age 1 year in the Pediatric Health Information System from 1999 to 2011 were included. IHR after the index hospitalization was considered delayed. Inter-hospital variability in the proportion of delayed repairs and differences in outcomes for each group were compared. A propensity score matched analysis was performed to account for baseline differences between treatment groups.

resultsOf the 2030 patients identified, 32.9% underwent delayed IHR with significant variability in the proportion of patients having delayed repair across hospitals (p<0.0001). More patients in the delayed group had a congenital anomaly or received life supportive measures prior to IHR (all p<0.01), and 8.2% of patients undergoing delayed repair had a diagnosis of incarceration at repair. More patients in the early group underwent reoperation for hernia within 1 year (5.9% vs. 3.7%, p=0.02). Results were similar after performing a propensity score matched analysis.

conclusionsSignificant variability in practice exists between children's hospitals in the timing of IHR, with delayed repair associated with incarceration and early repair with a higher rate of reoperation.

Indexed as

FemaleHernia, InguinalHerniorrhaphyHumansInfantInfant, NewbornMaleOperative TimePropensity ScoreSecond-Look SurgeryTreatment OutcomeDelayed repairInguinal herniaInguinal hernia repairNeonatePHIS

Identifiers

PMID25598118
PMCPMC4298703
OpenAlexW1963933441

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.