ArticleAngewandte Chemie (International ed. in English)2015
General method for the synthesis of salicylic acids from phenols through palladium-catalyzed silanol-directed C-H carboxylation.
Article in Angewandte Chemie (International ed. in English), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Synthesis of Hydroxyaromatic Carboxylic Acids via Homogeneous Kolbe-Schmitt Carboxylation of Phenoxides.Molecules (Basel, Switzerland) · 2026Article
- Fun With Unusual Functional Groups: Sulfamates, Phosphoramidates, and Di-tert-butyl Silanols.European journal of organic chemistry · 2024Article
- Simple and Efficient Aromatic C-H Oxazolination.Precision chemistry · 2023Article
- Large Scale Epoxide Opening by a Pendant Silanol.Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals · 2023Article
- Highly Stereospecific Cyclizations of Homoallylic Silanols.The Journal of organic chemistry · 2022Article
- Unusual Rearrangement-Remercuration Reactions of Allylic Silanols.Organic chemistry frontiers : an international journal of organic chemistry · 2021Article
- Tethered Silanoxymercuration of Allylic Alcohols.Organic letters · 2020Article
- Silanol: a bifunctional group for peptide synthesis and late-stage functionalization.Chemical science · 2020Article
- Tertiary amine-directed and involved carbonylative cyclizations through Pd/Cu-cocatalyzed multiple C-X (X = H or N) bond cleavage.Chemical science · 2019Article
- A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.Chemical Society reviews · 2018Review
- Silicon-Tethered Strategies for C-H Functionalization Reactions.Accounts of chemical research · 2017Article
- A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis.Nature communications · 2017Article
- Catalytic Reductive ortho-C-H Silylation of Phenols with Traceless, Versatile Acetal Directing Groups and Synthetic Applications of Dioxasilines.Journal of the American Chemical Society · 2016Article
- The design of a readily attachable and cleavable molecular scaffold forChemical science · 2016Article
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2 authors.
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Abstract
A silanol-directed, palladium-catalyzed C-H carboxylation reaction of phenols to give salicylic acids has been developed. This method features high efficiency and selectivity, and excellent functional-group tolerance. The generality of this method was demonstrated by the carboxylation of estrone and by the synthesis of an unsymmetrically o,o'-disubstituted phenolic compound through two sequential C-H functionalization processes.
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Registered trials
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