Evidence map›Paper›PMID 25597458›Full record

ArticleJournal of the American Academy of Audiology2015

Continued maturation of the click-evoked auditory brainstem response in preschoolers.

Emily Spitzer, Travis White-Schwoch, Kali Woodruff Carr, Erika Skoe, Nina Kraus

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Academy of Audiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Click-evoked auditory brainstem responses and autism spectrum disorder: A meta-analytic review.Autism research : official journal of the International Society for Autism Research · 2018
    Pooled it
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  9. Wave IFrontiers in pediatrics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Emily SpitzerDepartment of Communication Sciences, Auditory Neuroscience Laboratory, www.brainvolts.northwestern.edu, Northwestern University, Evanston, IL.
Travis White-SchwochDepartment of Communication Sciences, Auditory Neuroscience Laboratory, www.brainvolts.northwestern.edu, Northwestern University, Evanston, IL.
Kali Woodruff CarrDepartment of Communication Sciences, Auditory Neuroscience Laboratory, www.brainvolts.northwestern.edu, Northwestern University, Evanston, IL.
Erika SkoeDepartment of Communication Sciences, Auditory Neuroscience Laboratory, www.brainvolts.northwestern.edu, Northwestern University, Evanston, IL; Current address: Department of Speech, Language, and Hearing Sciences, Department of Psychology Affiliate, Cognitive Science Program Affiliate, University of Connecticut, Storrs, CT.
Nina KrausDepartment of Communication Sciences, Auditory Neuroscience Laboratory, www.brainvolts.northwestern.edu, Northwestern University, Evanston, IL; Department of Neurobiology and Physiology, Department of Otolaryngology, Institute for Neuroscience, Northwestern University, Evanston, IL.
Northwestern University · USCommunications Technology Laboratory · US

Funding

A preschool biomarker for literacyR01HD069414 · NICHD · NORTHWESTERN UNIVERSITY · PI KRAUS, NINA · 2012 to 2016
$1.8M
NICHD NIH HHS R01 HD069414NICHD NIH HHS R01HD069414
6 · The paper itself

Abstract

backgroundClick-evoked auditory brainstem responses (ABRs) are a valuable tool for probing auditory system function and development. Although it has long been thought that the human auditory brainstem is fully mature by age 2 yr, recent evidence indicates a prolonged developmental trajectory. PURPOSE: The purpose of this study was to determine the time course of ABR maturation in a preschool population and fill a gap in the knowledge of development. RESEARCH

designUsing a cross-sectional design, we investigated the effect of age on absolute latencies, interwave latencies, and amplitudes (waves I, III, V) of the click-evoked ABR. STUDY SAMPLE: A total of 71 preschoolers (ages 3.12-4.99 yr) participated in the study. All had normal peripheral auditory function and IQ. DATA COLLECTION AND ANALYSIS: ABRs to a rarefaction click stimulus presented at 31/sec and 80 dB SPL (73 dB nHL) were recorded monaurally using clinically-standard recording and filtering procedures while the participant sat watching a movie. Absolute latencies, interwave latencies, and amplitudes were then correlated to age.

resultsDevelopmental changes were restricted to absolute latencies. Wave V latency decreased significantly with age, whereas wave I and III latencies remained stable, even in this restricted age range.

conclusionsThe ABR does not remain static after age 2 yr, as seen by a systematic decrease in wave V latency between ages 3 and 5 yr. This finding suggests that the human brainstem has a continued developmental time course during the preschool years. Latency changes in the age 3-5 yr range should be considered when using ABRs as a metric of hearing health.

Indexed as

Acoustic StimulationAuditory ThresholdChild, PreschoolCross-Sectional StudiesEvoked Potentials, Auditory, Brain StemFemaleHearingHearing TestsHumansMaleReaction Time

Identifiers

PMID25597458
PMCPMC4914390
OpenAlexW2334455476

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.