Evidence map›Paper›PMID 25597299›Full record

ArticleAdvanced healthcare materials2015

Collagen Scaffolds Incorporating Coincident Gradations of Instructive Structural and Biochemical Cues for Osteotendinous Junction Engineering.

Steven R Caliari, Daniel W Weisgerber, William K Grier, Ziad Mahmassani, Marni D Boppart, Brendan A C Harley

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
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  4. Shaping the mechanical properties of a gelatin hydrogel interface via amination.Journal of the mechanical behavior of biomedical materials · 2026
    Article
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  6. Article
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  8. Review
  9. Article
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  11. Article
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  14. Review
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  16. Article
  17. Bioinspired Scaffold Designs for Regenerating Musculoskeletal Tissue Interfaces.Regenerative engineering and translational medicine · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Steven R CaliariDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 104 RAL, 600 S. Mathews Ave., Urbana, IL, 61801, USA.
Daniel W Weisgerber
William K Grier
Ziad Mahmassani
Marni D Boppart
Brendan A C Harley

Funding

Training Program in Chemistry-Interface with BiologyT32GM070421 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI HERGENROTHER, PAUL · 2005 to 2019
$5.4M
Patterning instructive biomolecular cues into collagen scaffolds for tendon inserR21AR063331 · NIAMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HARLEY, BRENDAN A. · 2013 to 2014
$359k
NIAMS NIH HHS R21 AR063331NIGMS NIH HHS T32 GM 070421NIGMS NIH HHS T32 GM070421
6 · The paper itself

Abstract

A fully 3D biomaterial containing overlapping gradations of structural, compositional, and biomolecular cues as seen in native orthopedic interfaces is described for the first time. A multi-compartment collagen scaffold is created for engineering tendon-bone junctions connected by a continuous interface that can induce spatially specific MSC differentiation down tenogenic and osteogenic lineages without the use of differentiation media.

Indexed as

Tissue EngineeringTissue ScaffoldsBone and BonesCollagenHumansTendonsCollagenbonecollagenmesenchymal stem cellsorthopedic interfacestendon

Identifiers

PMID25597299
PMCPMC4409544

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.