ArticleCurrent reviews in musculoskeletal medicine2015
Management of Propionibacterium acnes infection after shoulder surgery.
Article in Current reviews in musculoskeletal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03853096 (Do Intra-incisional Subdermal Antibiotics Alter the Colony Count of P. Acnes), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Do Intra-incisional Subdermal Antibiotics Alter the Colony Count of P. Acnes
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Optimized use and performance of culture for periprosthetic joint infection diagnosis: a comprehensive literature review.Clinical microbiology reviews · 2025Pooled it
- Assessment of a painful shoulder arthroplasty.Journal of clinical orthopaedics and trauma · 2025Article
- Hyperhidrosis increases the risk of postoperative infections after shoulder arthroplasty and rotator cuff repair.JSES international · 2025Article
- Subclinical Presentation of Cutibacterium acnes Infection Following Revision Rotator Cuff Surgery.Cureus · 2025Article
- Management of periprosthetic joint infection of the shoulder: A narrative review.Journal of clinical orthopaedics and trauma · 2024Article
- Risk factors for cardiac implantable electronic device infections: a nationwide Danish study.European heart journal · 2022Article
- Evaluation of the effectiveness of skin preparation methods for the reduction ofShoulder & elbow · 2022Review
- Ultrasound evaluations and guided procedures of the painful joint arthroplasty.Skeletal radiology · 2022Review
- Short-term outcomes of two-stage reverse total shoulder arthroplasty with antibiotic-loaded cement spacer for shoulder infection.Clinics in shoulder and elbow · 2022Article
- The management of the shoulder skin microbiome (Shoulder & elbow · 2021Article
- Risk factors for increased shoulderJSES international · 2020Article
- The In Vitro Efficacy of Doxycycline over Vancomycin and Penicillin in the Elimination ofAntimicrobial combination devices · 2020Article
- Article
- Capsular needle biopsy as a pre-operative diagnostic test for peri-prosthetic shoulder infection.Shoulder & elbow · 2019Article
- Reduced Time to PositiveJournal of shoulder and elbow arthroplasty · 2019Article
- Polymicrobial anaerobic infection with a deep abscess in the supraspinous fossa following a subacromial corticosteroid injection.BMJ case reports · 2018Article
- Article
- Ten questions on prosthetic shoulder infection.Shoulder & elbow · 2016Review
- Calcium sulphate mixed with antibiotics does not decrease efficacy againstJournal of orthopaedicsArticle
- Propionibacterium acnes Infection of the Shoulder After a Manipulation Under Anesthesia for Stiffness Status Post Open Reduction and Internal Fixation Proximal Humerus: A Case Report.Journal of orthopaedic case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Propionibacterium acnes (P. acnes) is a gram-positive anaerobic bacillus commonly isolated from the flora of the face, chest, and axilla region. It has emerged as a major pathogen responsible for postoperative shoulder infections after both arthroscopy and arthroplasty procedures. Patients with P. acnes shoulder infection typically present with normal laboratory values (white blood cells (WBC), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP)) making diagnosis difficult. Several intraoperative tissue cultures should be obtained and cultured in both agar plate and broth in aerobic and anaerobic conditions for a minimum of 13 days to optimize the sensitivity and specificity to detect P. acnes. The utilization of intraoperative frozen sections to detect P. acnes infection is not reliable. Risk factors include male, cloudy synovial fluid, lucencies around the implant, and periprosthetic membrane formation. Managements include irrigation and debridement, single or two-staged revision, and intravenous antibiotics. Open biopsy prior to the final implantation (two-staged revision) may help detect persistent P. acnes infection. Penicillin and cephalosporins are effective against clinical P. acnes infection and biofilm in vitro. Combination antibiotic therapy with rifampin and daptomycin may further increase the clinical efficacy of treatment.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.