Evidence map›Paper›PMID 25595748›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

Point-of-prescription interventions to improve antimicrobial stewardship.

Keith W Hamilton, Jeffrey S Gerber, Rebekah Moehring, Deverick J Anderson, Michael S Calderwood, Jennifer H Han, Jimish M Mehta, Lori A Pollack, Theoklis Zaoutis, Arjun Srinivasan and 4 more

Abstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Value of hospital antimicrobial stewardship programs [ASPs]: a systematic review.Antimicrobial resistance and infection control · 2019
    Pooled it
  2. Pooled it
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  10. Observational
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  12. Hospital-onset Clostridium difficile infection among solid organ transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Keith W HamiltonDivision of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia.
Jeffrey S GerberDivision of Infectious Diseases, Children's Hospital of Philadelphia, Pennsylvania.
Rebekah MoehringDivision of Infectious Diseases, Duke University Medical Center Duke Antimicrobial Stewardship Outreach Network, Durham, North Carolina.
Deverick J AndersonDivision of Infectious Diseases, Duke University Medical Center Duke Antimicrobial Stewardship Outreach Network, Durham, North Carolina.
Michael S CalderwoodDivision of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts.
Jennifer H HanDivision of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia.
Jimish M MehtaNorth American Medical Affairs, GlaxoSmithKline, Philadelphia, Pennsylvania.
Lori A PollackDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Theoklis ZaoutisDivision of Infectious Diseases, Children's Hospital of Philadelphia, Pennsylvania.
Arjun SrinivasanDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Bernard C CaminsDivision of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri.
David N SchwartzDivision of Infectious Diseases, John H. Stroger Jr Hospital of Cook County, Chicago, Illinois.
Ebbing LautenbachDivision of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia.
Centers for Disease Control and Prevention Epicenters Program

Funding

Defining Measures of Impact for Antimicrobial Stewardship Programs in Community HospitalsK08HS023866 · AHRQ · DUKE UNIVERSITY · PI MOEHRING, REBEKAH WHITE · 2015 to 2019
$739k
Clinical and Molecular Epidemiology of Multidrug-Resistant Organisms in a CommuniK23AI095357 · NIAID · DUKE UNIVERSITY · PI ANDERSON, DEVERICK JOHN · 2011 to 2015
$644k
AHRQ HHS K08 HS023866NCEZID CDC HHS FOA CK11-001NIAID NIH HHS K23 AI095357
6 · The paper itself

Abstract

Antimicrobial stewardship is pivotal to improving patient outcomes, reducing adverse events, decreasing healthcare costs, and preventing further emergence of antimicrobial resistance. In an era in which antimicrobial resistance is increasing, judicious antimicrobial use is the responsibility of every healthcare provider. Antimicrobial stewardship programs (ASPs) have made headway in improving antimicrobial prescribing using such "top-down" methods as formulary restriction and prospective audit with feedback; however, engagement of prescribers has not been fully explored. Strategies that include frontline prescribers and other unit-based healthcare providers have the potential to expand stewardship, both to augment existing centralized ASPs and to provide alternative approaches to perform stewardship at healthcare facilities with limited resources. This review discusses interventions focusing on antimicrobial prescribing at the point of prescription as well as a pilot project to engage unit-based healthcare providers in antimicrobial stewardship.

Indexed as

Anti-Infective AgentsCommunicable DiseasesDrug PrescriptionsDrug Resistance, MultipleDrug UtilizationHumansAnti-Infective Agentsantimicrobial prescribingantimicrobial stewardshipfrontlinepoint of prescription

Identifiers

PMID25595748
PMCPMC4415059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.