ArticleBMC infectious diseases2015
Patterns of HIV, TB, and non-communicable disease multi-morbidity in peri-urban South Africa- a cross sectional study.
Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06248190 (Effectiveness of a Health Systems Strengthening Intervention to Improve Detection, Treatment, and Control of Multiple Long-Term Conditions in Primary Health Care Facilities in the Western Cape and KwaZulu Natal, South Africa), which is not on this map. Cited by 120 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of a Health Systems Strengthening Intervention to Improve Detection, Treatment, and Control of Multiple Long-Term Conditions in Primary Health Care Facilities in the Western Cape and KwaZulu Natal, South Africa
Who cites it
120 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Prevalence of obesity, hypertension and diabetes among people living with HIV in South Africa: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- Prevalence of cardiovascular risk factors in active tuberculosis in Africa: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- A systematic review of engagement in care and health care utilization among older adults living with HIV and non-communicable diseases.AIDS care · 2022Pooled it
- Pooled it
- The association between HIV and atherosclerotic cardiovascular disease in sub-Saharan Africa: a systematic review.BMC public health · 2017Pooled it
- Trial
- Burden of Diagnosed Diabetes among People With and Without HIV in Uganda: a Cross-Sectional Analysis of the Rakai Community Cohort Study.Research square · 2026Article
- Patterns of Infectious Disease Identified in Clinical Autopsy at a South African Tertiary Care Setting: A 10-Year Retrospective Study.Diseases (Basel, Switzerland) · 2026Article
- Multimorbidity patterns, sociodemographic characteristics, and mortality: Data science insights from low-resource settings.American journal of epidemiology · 2026Article
- Prevalence and determinants of cardiometabolic comorbidities among people living with HIV receiving antiretroviral therapy at Zewditu Memorial Hospital: evidence from Ethiopia's longest serving AIDS clinic.BMC infectious diseases · 2026Article
- Prevalence and Correlates of Hyperglycemia Among People Living With HIV and TB on Dolutegravir-Based Antiretroviral Therapy in Zimbabwe: A Cross-Sectional Study.Health science reports · 2025Article
- An exploratory study of context and factors shaping policies for integrated management of multimorbidity in Malawi.Health research policy and systems · 2025Article
- Multimorbidity Management: A Scoping Review of Interventions and Health Outcomes.International journal of environmental research and public health · 2025Article
- Multimorbid life expectancy across race, socio-economic status, and sex in South Africa.Population studies · 2025Article
- Multimorbidity patterns and function among adults in low- and middle-income countries: a scoping review.BMJ open · 2025Article
- Multimorbidity in tuberculosis (TB) and its impact on patient care (MITICare): a cross-sectional study nested within a prospective cohort study protocol.Wellcome open research · 2025Article
- Predicting and improving diagnosis of tuberculosis outcomes in South Africa using machine learning techniques.PLOS global public health · 2025Article
- Prevalence, patterns, and determinants of multimorbidity in South Africa: Insights from a nationally representative survey.PLOS global public health · 2025Article
- Effectiveness of nurse-led multi-component intervention program (NLMIP) on improving antiretroviral therapy adherence, CDJournal of education and health promotion · 2025Article
- Digital Health Interventions for Adolescents with Long-Term Health Conditions in South Africa: A Scoping Review.International journal of environmental research and public health · 2024Article
60 more citing papers are in PubMed but not listed here.
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6 authors.
Funding
Abstract
backgroundMany low and middle-income countries are experiencing colliding epidemics of chronic infectious (ID) and non-communicable diseases (NCD). As a result, the prevalence of multiple morbidities (MM) is rising.
methodsWe conducted a study to describe the epidemiology of MM in a primary care clinic in Khayelitsha. Adults with at least one of HIV, tuberculosis (TB), diabetes (DM), and hypertension (HPT) were identified between Sept 2012-May 2013 on electronic databases. Using unique patient identifiers, drugs prescribed across all facilities in the province were linked to each patient and each drug class assigned a condition.
resultsThese 4 diseases accounted for 45% of all prescription visits. Among 14364 chronic disease patients, HPT was the most common morbidity (65%). 22.6% of patients had MM, with an increasing prevalence with age; and a high prevalence among younger antiretroviral therapy (ART) patients (26% and 30% in 18-35 yr and 36-45 year age groups respectively). Among these younger ART patients with MM, HPT and DM prevalence was higher than in those not on ART.
conclusionsWe highlight the co-existence of multiple ID and NCD. This presents both challenges (increasing complexity and the impact on health services, providers and patients), and opportunities for chronic diseases screening in a population linked to care. It also necessitates re-thinking of models of health care delivery and requires policy interventions to integrate and coordinate management of co-morbid chronic diseases.
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