ArticleParasites & vectors2015
Helminth control in kennels: is the combination of milbemycin oxime and praziquantel a right choice?
Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Field efficacy of Febantel, Pyrantel embonate and Praziquantel (Drontal® Tasty) against naturally acquired intestinal helminths of hunting dogs in southern Italy.Parasites & vectors · 2025Article
- A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter.Pathogens (Basel, Switzerland) · 2022Article
- Mining and engineering exporters for titer improvement of macrolide biopesticides in Streptomyces.Microbial biotechnology · 2022Article
- Longitudinal study for anthelmintic efficacy against intestinal helminths in naturally exposed Lithuanian village dogs: critical analysis of feasibility and limitations.Parasitology research · 2018Article
- Leishmania infantum, Dirofilaria spp. and other endoparasite infections in kennel dogs in central Italy.Parasite (Paris, France) · 2018Article
- Efficacy of nitazoxanide to treat natural Giardia infections in dogs.Parasites & vectors · 2017Article
- Characterization of a pathway-specific activator of milbemycin biosynthesis and improved milbemycin production by its overexpression in Streptomyces bingchenggensis.Microbial cell factories · 2016Article
- Efficacy of a single dose of milbemycin oxime/praziquantel combination tablets, Milpro(®), against adult Echinococcus multilocularis in dogs and both adult and immature E. multilocularis in young cats.Parasitology research · 2016Article
- Dirofilaria immitis and Angiostrongylus vasorum: the contemporaneous detection in kennels.BMC veterinary research · 2015Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKennel dogs are at the high risk of infections with intestinal and extra-intestinal helminths. Therefore, regular parasitological surveillance, appropriate treatment strategies and high quality standard of hygiene are required to guarantee the health and welfare of kennel dogs. The aim of the present study was to evaluate the efficacy of helminth control in kennels using different broad-spectrum anthelmintics that are routinely used in canine veterinary practice. Particular attention was given to the field efficacy and ease-of-use of each product.
methodsThe study was conducted in 3 public kennels in the Campania region (southern Italy). Eighteen boxes from each of the three kennels were selected for treatment based on faecal egg counts (FECs) at Day -30. The treatments were conducted using tablets containing combinations of: i) milbemycin oxime and praziquantel (Milbemax®); ii) pyrantel embonate, febantel and praziquantel (Drontal Plus Flavour®), and; iii) pyrantel pamoate, oxantel pamoate and praziquantel (Nemex® POP). All dogs were treated on Day 0 and sampled on Days 0, 7, 14 and 21 for copromicroscopic analyses. The FLOTAC dual technique on pooled samples was used with efficacy determined by reduction in FECs.
resultsAt Day -30 intestinal nematodes (hookworms, Toxocara, Trichuris) and cestodes (Dypilidium caninum) were found. Milbemax® showed 100% efficacy against all the helminths in all the kennels. Drontal Plus Flavour® was 100% effective against hookworms in all the kennels but gave lower efficacy against T. canis (range=97.1-100%) and T. vulpis (range=95.6-100%). Nemex® POP was also 100% effective against hookworms in all kennels but less effective against T. canis (range=95.7-100%) and T. vulpis (range=95.7-100%). All three drugs were 100% effective against D.caninum.
conclusionsMilbemax®was fully effective against all the helminthes and was palatable and ease-of-use for all the dogs. It is the optimum choice for the treatment and prevention of helminth infections in kennel dogs under field conditions.
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