Trial reportManual therapy2015
Immediate changes in pressure pain sensitivity after thoracic spinal manipulative therapy in patients with subacromial impingement syndrome: A randomized controlled study.
Trial report in Manual therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06110039 (Comparative Effects of Cervicothoracic Junction Mobilization With Arm Movements and Upper Thoracic Manipulation in Patients With Subachromial Impinegment Syndrome), which is not on this map. Cited by 17 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effects of Cervicothoracic Junction Mobilization With Arm Movements and Upper Thoracic Manipulation in Patients With Subachromial Impinegment Syndrome
Who cites it
17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Does manual therapy meaningfully change quantitative sensory testing and patient reported outcome measures in patients with musculoskeletal impairments related to the spine?: A 'trustworthy' systematic review and meta-analysis.The Journal of manual & manipulative therapy · 2024Pooled it
- Is there 'trustworthy' evidence for using manual therapy to treat patients with shoulder dysfunction?: A systematic review.PloS one · 2024Pooled it
- Manual Therapy Effect in Placebo-Controlled Trials: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Effectiveness of cervicothoracic and thoracic manual physical therapy in managing upper quarter disorders - a systematic review.The Journal of manual & manipulative therapy · 2022Pooled it
- Manipulation-induced hypoalgesia in musculoskeletal pain populations: a systematic critical review and meta-analysis.Chiropractic & manual therapies · 2019Pooled it
- Manual therapy and exercise for rotator cuff disease.The Cochrane database of systematic reviews · 2016Pooled it
- Does adding cervical mobilization to shoulder mobilization improve pain, sensation, and function in subacromial impingement syndrome? A three-arm randomized controlled trial.BMC musculoskeletal disorders · 2026Trial
- The effect of manual therapy to the thoracic spine on pain-free grip and sympathetic activity in patients with lateral epicondylalgia humeri. A randomized, sample sized planned, placebo-controlled, patient-blinded monocentric trial.BMC musculoskeletal disorders · 2020Trial
- Effect of spinal manipulative therapy on mechanical pain sensitivity in patients with chronic nonspecific low back pain: a pilot randomized, controlled trial.The Journal of manual & manipulative therapy · 2020Trial
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- Effect of thoracic mobilization on acromio-humeral distance, thoracic kyphosis angle, pain and shoulder function in patients with subacromial impingement syndrome: A randomized controlled trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Evidence for increased neuromuscular drive following spinal manipulation in individuals with subacromial pain syndrome.Clinical biomechanics (Bristol, Avon) · 2021Article
- Screening of the cervical spine in subacromial shoulder pain: A systematic review.Shoulder & elbow · 2019Review
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- A systematic review of thrust manipulation combined with one conservative intervention for rotator cuff and related non-surgical shoulder conditions.The Journal of the Canadian Chiropractic Association · 2018Article
- A systematic review of thrust manipulation for non-surgical shoulder conditions.Chiropractic & manual therapies · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThoracic SMT can improve symptoms in patients with subacromial impingement syndrome. However, at this time the mechanisms of SMT are not well established. It is possible that changes in pain sensitivity may occur following SMT.
objectivesTo assess the immediate pain response in patients with shoulder pain following thoracic spinal manipulative therapy (SMT) using pressure pain threshold (PPT), and to assess the relationship of change in pain sensitivity to patient-rated outcomes of pain and function following treatment.
designRandomized Controlled Study.
methodsSubjects with unilateral subacromial impingement syndrome (n = 45) were randomly assigned to receive treatment with thoracic SMT or sham thoracic SMT. PPT was measured at the painful shoulder (deltoid) and unaffected regions (contralateral deltoid and bilateral lower trapezius areas) immediately pre- and post-treatment. Patient-rated outcomes were pain (numeric pain rating scale - NPRS), function (Pennsylvania Shoulder Score - Penn), and global rating of change (GROC).
resultsThere were no significant differences between groups in pre-to post-treatment changes in PPT (p ≥ 0.583) nor were there significant changes in PPT within either group (p ≥ 0.372) following treatment. NPRS, Penn and GROC improved across both groups (p < 0.001), but there were no differences between the groups (p ≥ 0.574).
conclusionThere were no differences in pressure pain sensitivity between participants receiving thoracic SMT versus sham thoracic SMT. Both groups had improved patient-rated pain and function within 24-48 h of treatment, but there was no difference in outcomes between the groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.