ArticleCerebral cortex (New York, N.Y. : 1991)2016
Functional Imaging of the Developing Brain at the Bedside Using Diffuse Optical Tomography.
Article in Cerebral cortex (New York, N.Y. : 1991), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05514665 (A Prospective Feasibility Study to Derive Novel Imaging Biomarker of Perinatal Brain Injury Based on Bedside Diffuse Optical Tomography in Neonates), which is not on this map. Cited by 74 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Feasibility Study to Derive Novel Imaging Biomarker of Perinatal Brain Injury Based on Bedside Diffuse Optical Tomography in Neonates
Who cites it
74 citing papers in PubMed.
- Cedalion tutorial: a Python-based framework for comprehensive analysis of multimodal fNIRS and DOT from the lab to the everyday world.Neurophotonics · 2026Article
- Disrupted functional connectivity during stroke recovery revealed via bedside optical neuroimaging.Neurophotonics · 2026Article
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- Robust photogrammetric scalp morphology estimation for functional optical neuroimaging.Neurophotonics · 2025Article
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- Continuous Wave-Diffuse Optical Tomography (CW-DOT) in Human Brain Mapping: A Review.Sensors (Basel, Switzerland) · 2025Review
- Functional brain mapping using whole-head very high-density diffuse optical tomography.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Multisensory naturalistic decoding with high-density diffuse optical tomography.Neurophotonics · 2025Article
- Bedside Neuroimaging Using High-Density Diffuse Optical Tomography in a Pediatric Patient on Extracorporeal Support.Stroke · 2025Article
- Multimodal fNIRS-EEG sensor fusion: Review of data-driven methods and perspective for naturalistic brain imaging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Mapping brain function underlying naturalistic motor observation and imitation using high-density diffuse optical tomography.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Sleep state-dependent development of resting-state functional connectivity during the preterm period.Sleep · 2024Article
- Investigating Task-Free Functional Connectivity Patterns in Newborns Using Functional Near-Infrared Spectroscopy.Brain and behavior · 2024Article
- Ecological functional near-infrared spectroscopy in mobile children: using short separation channels to correct for systemic contamination during naturalistic neuroimaging.Neurophotonics · 2024Article
- ninjaNIRS: an open hardware solution for wearable whole-head high-density functional near-infrared spectroscopy.Biomedical optics express · 2024Article
- Mapping neural correlates of biological motion perception in autistic children using high-density diffuse optical tomography.Molecular autism · 2024Article
- Distinct Time-Resolved Brain-Wide Coactivations in Oxygenated and Deoxygenated Hemoglobin.IEEE transactions on bio-medical engineering · 2024Article
- Mapping brain function in adults and young children during naturalistic viewing with high-density diffuse optical tomography.Human brain mapping · 2024Article
- Subject-specific information enhances spatial accuracy of high-density diffuse optical tomography.Frontiers in neuroergonomics · 2024Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
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Abstract
While histological studies and conventional magnetic resonance imaging (MRI) investigations have elucidated the trajectory of structural changes in the developing brain, less is known regarding early functional cerebral development. Recent investigations have demonstrated that resting-state functional connectivity MRI (fcMRI) can identify networks of functional cerebral connections in infants. However, technical and logistical challenges frequently limit the ability to perform MRI scans early or repeatedly in neonates, particularly in those at greatest risk for adverse neurodevelopmental outcomes. High-density diffuse optical tomography (HD-DOT), a portable imaging modality, potentially enables early continuous and quantitative monitoring of brain function in infants. We introduce an HD-DOT imaging system that combines advancements in cap design, ergonomics, and data analysis methods to allow bedside mapping of functional brain development in infants. In a cohort of healthy, full-term neonates scanned within the first days of life, HD-DOT results demonstrate strong congruence with those obtained using co-registered, subject-matched fcMRI and reflect patterns of typical brain development. These findings represent a transformative advance in functional neuroimaging in infants, and introduce HD-DOT as a powerful and practical method for quantitative mapping of early functional brain development in normal and high-risk neonates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.