ReviewSurvey of ophthalmology
Optic nerve lymphoma: report of two cases and review of the literature.
Review in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 54 citations in OpenAlex.
- Rapidly progressive primary vitreoretinal lymphoma with optic disc involvement and retinal detachment.American journal of ophthalmology case reports · 2026Article
- Orbital Neurolymphomatosis in Patient with CNS Lymphoma.Diagnostics (Basel, Switzerland) · 2025Article
- A rare case of infiltrative optic neuropathy caused by vitreoretinal lymphoma with hyperreflective deposits in the intraretinal and subretinal pigment epithelial layers prior to the disease onset.BMC ophthalmology · 2024Article
- Primary Central Nervous System Lymphoma Presenting as Optic Nerve Infiltration: A Case Report.Cureus · 2023Article
- Primary non-Hodgkin lymphoma of the chiasm and optic tract in a nonimmunocompromised patient: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Neoplastic nerve lesions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Review
- Article
- Magnetic resonance imaging of the orbit, Part 2: Characterization of orbital pathologies.Indian journal of ophthalmology · 2021Review
- Article
- Primary disease sites and patterns of spread in cases of neurolymphomatosis in the orbit associated with lymphoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Bilateral optic disc swelling resulting from lymphocytic meningitis and posterior uveitis secondary to syphilis.BMJ case reports · 2021Article
- Bilateral Simultaneous Lymphomatous Optic Nerve Infiltration in Sporadic Burkitt's Lymphoma.Neuro-ophthalmology (Aeolus Press) · 2021Article
- Swept Source Optical Coherence Tomography Documenting Optic Nerve Involvement in an Aggressive T-Cell Lymphoma.Neuro-ophthalmology (Aeolus Press) · 2021Article
- Perineuritis or infiltration of optic nerve sheath? A presentation of diffuse large B cell Gastric lymphoma.Indian journal of ophthalmology · 2020Article
- Stage IV Small Lymphocytic Lymphoma Presenting with Unilateral Vision Loss.Case reports in oncological medicine · 2020Article
- Orbital Magnetic Resonance Imaging May Contribute to the Diagnosis of Optic Nerve Lymphoma.Frontiers in neurology · 2020Article
- A Case of Compressive Optic Neuropathy Secondary to Lymphoma of the Extraocular Muscles.Neuro-ophthalmology (Aeolus Press) · 2019Article
- B-scan ultrasound and cytology of the vitreous in primary central nervous system lymphoma with vitreoretinal involvement.International journal of ophthalmology · 2019Article
- Ethics of a therapeutic trial: addressing limitations of an active intervention in optic nerve lymphoma.BMJ case reports · 2018Article
- Macular ganglion cell complex measurement in bilateral retrobulbar optic neuropathy without a relative afferent pupillary defect.International medical case reports journal · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Lymphoma may involve the optic nerve as isolated optic nerve lymphoma or in association with central nervous system (CNS) or systemic lymphoma. We present two biopsy-proven non-Hodgkin lymphomas of the optic nerve and compare our findings with previously reported cases. We discuss the mechanism of metastasis, classification of optic nerve involvement, clinical features, radiologic findings, optic nerve biopsy indications and techniques, histologic features, and treatments. We propose a classification system of optic nerve lymphoma: isolated optic nerve involvement, optic nerve involvement with CNS disease, optic nerve involvement with systemic disease, and optic nerve involvement with primary intraocular lymphoma. Although it is an uncommon cause of infiltrative optic neuropathy, optic nerve metastasis should be considered in patients with a history of lymphoma. The recommended approach to a patient with presumed optic nerve lymphoma includes neuroimaging and cerebrospinal fluid evaluation as part of the initial workup, then judicious use of optic nerve biopsy, depending on the clinical situation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.