Evidence map›Paper›PMID 25594643›Full record

Observational studyInternational surgery2015

Emergency presenting colon cancer is an independent predictor of adverse disease-free survival.

John Hogan, Georges Samaha, John Burke, Kah Hoong Chang, Eoghan Condon, David Waldron, John Calvin Coffey

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in International surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Blood urea nitrogen-to-albumin ratio as a predictor of mortality in patients undergoing emergency surgery for obstructive colon cancer.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
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  4. Article
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  6. Surgical outcomes of curative intent management in emergency vs. elective colon cancer: A retrospective single center study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  7. Article
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  10. Article
  11. Article
  12. Article
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  14. Review
  15. Article
  16. Article
  17. Extent of Surgical Resection in Inflammatory Bowel Disease Associated Colorectal Cancer: a Population-Based Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

John Hogan1 Department of Colorectal Surgery, University Hospital Limerick, Ireland.
Georges Samaha
John Burke
Kah Hoong Chang
Eoghan Condon
David Waldron
John Calvin Coffey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty percent of colon cancers present as an emergency. However, the association between emergency presentation and disease-free survival (DFS) remains uncertain. Consecutive patients who underwent elective (CC) and emergent (eCC) resection for colon cancer were included in the analysis. Survival outcomes were compared between the 2 groups in univariate/multivariate analyses. A total of 439 patients underwent colonic resection for colon cancer during the interval 2000-2010; 97 (22.1%) presented as an emergency. eCC tumors were more often located at the splenic flexure (P = 0.017) and descending colon (P = 0.004). The eCC group displayed features of more advanced disease with a higher proportion of T4 (P = 0.009), N2 tumors (P < 0.01) and lymphovascular invasion (P< 0.01). eCC was associated with adverse locoregional recurrence (P = 0.02) and adverse DFS (P < 0.01 ) on univariate analysis. eCC remained an independent predictor of adverse locoregional recurrence (HR 1.86, 95% CI 1.50-3.30, P = 0.03) and DFS (HR 1.30, 95% CI 0.88-1.92, P = 0.05) on multivariate analysis. eCC was not associated with adverse overall survival and systemic recurrence. eCC is an independent predictor of adverse locoregional recurrence and DFS.

Indexed as

ColectomyAdenocarcinomaAgedColonic NeoplasmsDisease-Free SurvivalEmergenciesFemaleFollow-Up StudiesHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasm StagingColon cancerDisease free survivalEmergency presentationLocoregional recurrence

Identifiers

PMID25594643
PMCPMC4301297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.