Evidence map›Paper›PMID 25594634›Full record

ArticleInternational surgery2015

Should subtotal thyroidectomy be abandoned in multinodular goiter patients from endemic regions requiring surgery?

Tayfun Yoldas, Ozer Makay, Gokhan Icoz, Timur Kose, Gulten Gezer, Erkan Kismali, Sadık Tamsel, Sureyya Ozbek, Mustafa Yılmaz, Mahir Akyildiz

Open access · bronzeAbstract readComparative StudyEvaluation Study
In one paragraph

Article in International surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Follicular-Patterned Lesions of the Thyroid Gland.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2026
    Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Substernal Goiter: From Definitions to Treatment.Sisli Etfal Hastanesi tip bulteni · 2022
    Review
  11. An overview of retrosternal goiter.Journal of endocrinological investigation · 2021
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tayfun Yoldas1 School of Medicine, Department of General Surgery, Division Endocrine Surgery, Ege University, Izmir, Turkey.
Ozer Makay
Gokhan Icoz
Timur Kose
Gulten Gezer
Erkan Kismali
Sadık Tamsel
Sureyya Ozbek
Mustafa Yılmaz
Mahir Akyildiz
Ege University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most convenient surgical procedure for benign thyroid diseases is still controversial. The aim of this study is to determine the recurrence rate and risk factors for recurrence after different thyroidectomy procedures in multinodular goiter patients. Patients were separated into two groups according to the detection of a recurrent nodule or not after thyroidectomy. Of the 748 patients, 216 (29%) had recurrence, while 532 had no recurrent nodule. The difference between surgical procedures described as subtotal (ST), near total (NT) and total thyroidectomy (TT) was statistically significant. Transient hypoparathyroidism was significantly higher in NT and TT, when compared to ST patients (P < 0.05). Young age, bilateral multinodular goiter and insufficient surgery are risk factors affecting recurrence for benign nodular thyroid disease. Currently, subtotal procedures should be discontinued and total or near total procedures should be preferred. Meanwhile, the probability of a higher risk of hypoparathyroidism should be kept in mind.

Indexed as

Endemic DiseasesAdultFemaleFollow-Up StudiesGoiter, NodularHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsThyroidectomyTreatment OutcomeTurkeyMultinodular goiterRecurrence classification description: EndocrinologyThyroidectomy

Identifiers

PMID25594634
PMCPMC4301299
OpenAlexW2067421056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.