Evidence map›Paper›PMID 25594439›Full record

ReviewNutrients2015

Dietary strategies for the treatment of cadmium and lead toxicity.

Qixiao Zhai, Arjan Narbad, Wei Chen

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 1 pooled it
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 1 synthesis or guideline pooled it, 308 citations in OpenAlex.

  1. Pooled it
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  10. Preparation of silibinin- dendrimer-stabilized Au nanoparticles for decreasing vancomycin resistance in S. aureus clinical isolates.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Qixiao ZhaiState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 LiHu Road, Wuxi 214122, China. zhaiqixiao@sina.com.
Arjan NarbadGut Health and Food Safety Programme, Institute of Food Research, Norwich NR4 7UA, UK. arjan.narbad@ifr.ac.uk.
Wei ChenState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 LiHu Road, Wuxi 214122, China. chenwei66@jiangnan.edu.cn.
Jiangnan University · CNQuadram Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/F/00044437Biotechnology and Biological Sciences Research Council BBS/E/F/00044453Biotechnology and Biological Sciences Research Council BBS/OS/NW/000006
6 · The paper itself

Abstract

Cadmium (Cd) and lead (Pb) are toxic heavy metals that cause adverse health effects in humans and animals. Chelation therapy, the conventional treatment for heavy metal toxicity, is reported to have a number of safety and efficacy issues. Recent studies have shown that dietary supplements play important roles in protecting against Cd and Pb toxicity. This paper reviews the evidence for protective effects of essential metals, vitamins, edible plants, phytochemicals, probiotics and other dietary supplements against Cd and Pb toxicity and describes the proposed possible mechanisms. Based on these findings, dietary strategies are recommended for people at risk of Cd and Pb exposure. The application of these strategies is advantageous for both the prevention and alleviation of Cd and Pb toxicity, as such supplements can be added easily and affordably to the daily diet and are expected to have very few side effects compared to the chelation therapy.

Indexed as

Heavy Metal PoisoningAnimalsCadmiumDietary SupplementsDisease Models, AnimalFunctional FoodHumansLeadPhytochemicalsPlants, EdiblePoisoningProbioticsTrace ElementsVitaminsCadmiumLeadPhytochemicalsTrace ElementsVitamins

Identifiers

PMID25594439
PMCPMC4303853
OpenAlexW2083832602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.