Evidence map›Paper›PMID 25594438›Full record

ReviewNutrients2015

Nutritionally-induced catch-up growth.

Galia Gat-Yablonski, Moshe Phillip

Abstract readReview
In one paragraph

Review in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Trial
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  7. Review
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  17. Observational
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  19. Chronic kidney disease in children: an update.Clinical kidney journal · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Galia Gat-YablonskiThe Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Children's Diabetes, Schneider Children's Medical Center of Israel, and Felsenstein Medical Research Center, Petach Tikva 49100, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel. galiagy@post.tau.ac.il.
Moshe PhillipThe Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Children's Diabetes, Schneider Children's Medical Center of Israel, and Felsenstein Medical Research Center, Petach Tikva 49100, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel. mosheph@post.tau.ac.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malnutrition is considered a leading cause of growth attenuation in children. When food is replenished, spontaneous catch-up (CU) growth usually occurs, bringing the child back to its original growth trajectory. However, in some cases, the CU growth is not complete, leading to a permanent growth deficit. This review summarizes our current knowledge regarding the mechanism regulating nutrition and growth, including systemic factors, such as insulin, growth hormone, insulin- like growth factor-1, vitamin D, fibroblast growth factor-21, etc., and local mechanisms, including autophagy, as well as regulators of transcription, protein synthesis, miRNAs and epigenetics. Studying the molecular mechanisms regulating CU growth may lead to the establishment of better nutritional and therapeutic regimens for more effective CU growth in children with malnutrition and growth abnormalities. It will be fascinating to follow this research in the coming years and to translate the knowledge gained to clinical benefit.

Indexed as

AutophagyChildEpigenomicsFibroblast Growth FactorsGlucocorticoidsGrowth DisordersGrowth HormoneHumansHypoxia-Inducible Factor 1, alpha SubunitInfantInsulinInsulin-Like Growth Factor ILeptinMalnutritionMicroRNAsNutritional Statusfibroblast growth factor 21Fibroblast Growth FactorsGlucocorticoidsGrowth HormoneHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitInsulinInsulin-Like Growth Factor ILeptinMicroRNAsMTOR protein, humanThyroid HormonesTOR Serine-Threonine KinasesVitamin D

Identifiers

PMID25594438
PMCPMC4303852

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.