ArticleCell2015
Disentangling inborn and acquired immunity in human twins.
Article in Cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Human Genomics of COVID-19 Pneumonia: Contributions of Rare and Common Variants.Annual review of biomedical data science · 2023Review
- Human genetics of infectious diseases: Unique insights into immunological redundancy.Seminars in immunology · 2018Review
- Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.Nature immunology · 2018Article
- Monozygotic twins with GATA2 deficiency: same haploidentical-related donor, different severity of GvHD.Bone marrow transplantation · 2017Article
- Age-Dependent Association ofFrontiers in immunology · 2017Article
- Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.American journal of human genetics · 2016Article
- Comparison of Human Neonatal and Adult Blood Leukocyte Subset Composition Phenotypes.PloS one · 2016Article
- Severe infectious diseases of childhood as monogenic inborn errors of immunity.Proceedings of the National Academy of Sciences of the United States of America · 2015Review
- Anti-cytokine autoantibodies in postherpetic neuralgia.Journal of translational medicine · 2015Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human geneticist Archibald Garrod noted in 1931 that, "It is, of necessity, no easy matter to distinguish between immunity which is inborn and that which has been acquired" (The Inborn Factors in Disease). In this issue of Cell, Brodin et al. show that the heritability of blood counts rapidly decreases with age for the lymphoid subsets responsible for adaptive immunity, unlike cells from other hematopoietic lineages.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.