ReviewFrontiers in surgery2014
Somatic stem cells and their dysfunction in endometriosis.
Review in Frontiers in surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Three-Dimensional Architecture of Ectopic Epithelium and Vasculature in Ovarian Endometriosis Revealed by Tissue-Clearing Imaging.Cell proliferation · 2026Article
- Stromal-only endometriosis catamenial pneumothorax: A diagnostic algorithm with potential pitfalls.Virchows Archiv : an international journal of pathology · 2026Article
- Pain pathways and stem cells in endometriosis pathogenesis.Molecular biology reports · 2025Review
- Comprehensive Management of Bowel Endometriosis: Surgical Techniques, Outcomes, and Best Practices.Journal of clinical medicine · 2025Review
- Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.npj women's health · 2025Review
- Different Effect of Dienogest on Endometrium Mesenchymal Stem Cells Derived from Healthy and Endometriosis TissuesBalkan medical journal · 2024Article
- Primary Extrapelvic Umbilical Endometriosis Presenting With Cyclical Umbilical Bleeding: A Case Report.Cureus · 2024Article
- The Main Theories on the Pathogenesis of Endometriosis.International journal of molecular sciences · 2023Review
- Circulating Endometrial Cells: A New Source of Information on Endometriosis Dynamics.Journal of clinical medicine · 2019Article
- EXTL3-interacting endometriosis-specific serum factors induce colony formation of endometrial stromal cells.Scientific reports · 2019Article
- FOXP1 enhances fibrosis via activating Wnt/β-catenin signaling pathway in endometriosis.American journal of translational research · 2018Article
- Commentary: Somatic Stem Cells and Their Dysfunction in Endometriosis.Frontiers in surgery · 2017Article
- Evaluation of two endometriosis models by transplantation of human endometrial tissue fragments and human endometrial mesenchymal cells.International journal of reproductive biomedicine · 2017Article
- [Research progress on the role of epithelial-mesenchymal transition in pathogenesis of endometriosis].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2016Review
- The Role of Stem Cells in the Etiology and Pathophysiology of Endometriosis.Seminars in reproductive medicine · 2015Review
- Pathogenesis of Endometriosis: Focus on Adenogenesis-related Factors.In vivo (Athens, Greece)Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidence indicates that somatic stem cells (SSCs) of different types prominently contribute to endometrium-associated disorders such as endometriosis. We reviewed the pertinent studies available on PubMed, published in English language until December 2014 and focused on the involvement of SSCs in the pathogenesis of this common gynecological disease. A concise summary of the data obtained from in vitro experiments, animal models, and human tissue analyses provides insights into the SSC dysregulation in endometriotic lesions. In addition, a set of research results is presented supporting that SSC-targeting, in combination with hormonal therapy, may result in improved control of the disease, while a more in-depth characterization of endometriosis SSCs may contribute to the development of early-disease diagnostic tests with increased sensitivity and specificity. Key message: Seemingly essential for the establishment and progression of endometriotic lesions, dysregulated SSCs, and associated molecular alterations hold a promise as potential endometriosis markers and therapeutic targets.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.