ArticleGenome medicine2014
Genomics and infectious disease: a call to identify the ethical, legal and social implications for public health and clinical practice.
Article in Genome medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 40 citations in OpenAlex.
- The Impact of Transmissible Microbes: How the Cystic Fibrosis Community Mobilized Against Cepacia.Perspectives in biology and medicine · 2023Article
- VBEBioMedicine · 2021Article
- Governing Personalized Health: A Scoping Review.Frontiers in genetics · 2021Article
- Genomics in the era of COVID-19: ethical implications for clinical practice and public health.Genome medicine · 2020Article
- What If the Influenza Vaccine Did Not Offer Such Variable Protection?The Journal of infectious diseases · 2020Article
- Just data? Solidarity and justice in data-driven medicine.Life sciences, society and policy · 2020Article
- Microbial genomics amidst the Arctic crisis.Microbial genomics · 2020Review
- Genomics and Infectious Diseases: Expert Perspectives on Public Health Considerations regarding Actionability and Privacy.Ethics & human research · 2020Article
- Ethical challenges in pathogen sequencing: a systematic scoping review.Wellcome open research · 2020Article
- Trust and the ethical challenges in the use of whole genome sequencing for tuberculosis surveillance: a qualitative study of stakeholder perspectives.BMC medical ethics · 2019Article
- Societal Implications of the Internet of Pathogens.Journal of clinical microbiology · 2019Article
- Ethical considerations in global HIV phylogenetic research.The lancet. HIV · 2018Review
- Towards a genomics-informed, real-time, global pathogen surveillance system.Nature reviews. Genetics · 2018Review
- Genomics in Patient Care and Workforce Decisions in High-Level Isolation Units: A Survey of Healthcare Workers.Health securityArticle
- Genomics and High-Consequence Infectious Diseases: A Scoping Review of Emerging Science and Potential Ethical Issues.Health securityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Advances in genomics are contributing to the development of more effective, personalized approaches to the prevention and treatment of infectious diseases. Genetic sequencing technologies are furthering our understanding of how human and pathogen genomic factors - and their interactions - contribute to individual differences in immunologic responses to vaccines, infections and drug therapies. Such understanding will influence future policies and procedures for infectious disease management. With the potential for tailored interventions for particular individuals, populations or subpopulations, ethical, legal and social implications (ELSIs) may arise for public health and clinical practice. Potential considerations include balancing health-related benefits and harms between individuals and the larger community, minimizing threats to individual privacy and autonomy, and ensuring just distribution of scarce resources. In this Opinion, we consider the potential application of pathogen and host genomic information to particular viral infections that have large-scale public health consequences but differ in ELSI-relevant characteristics such as ease of transmission, chronicity, severity, preventability and treatability. We argue for the importance of anticipating these ELSI issues in advance of new scientific discoveries, and call for the development of strategies for identifying and exploring ethical questions that should be considered as clinical, public health and policy decisions are made.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.