ArticleSoft matter
Enhanced activity of cyclic transporter sequences driven by phase behavior of peptide-lipid complexes.
Article in Soft matter. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- How Do Biomolecules Cross the Cell Membrane?Accounts of chemical research · 2022Article
- Machine learning antimicrobial peptide sequences: Some surprising variations on the theme of amphiphilic assembly.Current opinion in colloid & interface science · 2018Article
- Article
- Self-assembling amphiphilic peptides.Journal of peptide science : an official publication of the European Peptide Society · 2014Review
- Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery.Biochemistry · 2014Article
- Interaction between a cationic surfactant-like peptide and lipid vesicles and its relationship to antimicrobial activity.Langmuir : the ACS journal of surfaces and colloids · 2013Article
- A critical evaluation of random copolymer mimesis of homogeneous antimicrobial peptides.Macromolecules · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We demonstrate that recent observed increases in cell permeation activity of cyclic peptides via transporter sequences is due to the underlying phase behavior of peptide-lipid complexes and its relation to the topological requirement of membrane permeation. We also show how these effects can be amplified by incorporating hydrophobicity in these sequences.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.