Evidence map›Paper›PMID 25593549›Full record

ArticleNanoscale research letters2014

Chemical and magnetic functionalization of graphene oxide as a route to enhance its biocompatibility.

Karolina Urbas, Malgorzata Aleksandrzak, Magdalena Jedrzejczak, Malgorzata Jedrzejczak, Rafal Rakoczy, Xuecheng Chen, Ewa Mijowska

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Article
  3. The Influence of Graphene Oxide-FeInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Adsorptive and photocatalytic activity of FeEnvironmental science and pollution research international · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Karolina UrbasInstitute of Chemical and Environment Engineering, West Pomeranian University of Technology, Szczecin, Piastow Avenue 45, Szczecin 70-311, Poland.
Malgorzata AleksandrzakInstitute of Chemical and Environment Engineering, West Pomeranian University of Technology, Szczecin, Piastow Avenue 45, Szczecin 70-311, Poland.
Magdalena JedrzejczakLaboratory of Cytogenetics, West Pomeranian University of Technology, Szczecin, Judyma 6, Szczecin 71-466, Poland.
Malgorzata JedrzejczakLaboratory of Cytogenetics, West Pomeranian University of Technology, Szczecin, Judyma 6, Szczecin 71-466, Poland.
Rafal RakoczyInstitute of Chemical Engineering and Environmental Protection Process, West Pomeranian University of Technology, Szczecin, Piastow Avenue 42, Szczecin 71-065, Poland.
Xuecheng ChenInstitute of Chemical and Environment Engineering, West Pomeranian University of Technology, Szczecin, Piastow Avenue 45, Szczecin 70-311, Poland.
Ewa MijowskaInstitute of Chemical and Environment Engineering, West Pomeranian University of Technology, Szczecin, Piastow Avenue 45, Szczecin 70-311, Poland.
West Pomeranian University of Technology · PLInstitute of Chemical Engineering · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel approach for deposition of iron oxide nanoparticles with narrow size distribution supported on different sized graphene oxide was reported. Two different samples with different size distributions of graphene oxide (0.5 to 7 μm and 1 to 3 μm) were selectively prepared, and the influence of the flake size distribution on the mitochondrial activity of L929 with WST1 assay in vitro study was also evaluated. Little reduction of mitochondrial activity of the GO-Fe3O4 samples with broader size distribution (0.5 to 7 μm) was observed. The pristine GO samples (0.5 to 7 μm) in the highest concentrations reduced the mitochondrial activity significantly. For GO-Fe3O4 samples with narrower size distribution, the best biocompatibility was noticed at concentration 12.5 μg/mL. The highest reduction of cell viability was noted at a dose 100 μg/mL for GO (1 to 3 μm). It is worth noting that the chemical functionalization of GO and Fe3O4 is a way to enhance the biocompatibility and makes the system independent of the size distribution of graphene oxide.

Indexed as

BiocompatibilityGraphene oxideMagnetic nanoparticles

Identifiers

PMID25593549
PMCPMC4273676
OpenAlexW2130743761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.