Evidence map›Paper›PMID 25593454›Full record

ReviewWorld journal of gastroenterology2015

Role of the diet as a link between oxidative stress and liver diseases.

Teresa Arrigo, Salvatore Leonardi, Caterina Cuppari, Sara Manti, Angela Lanzafame, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 52 citations in OpenAlex.

  1. The paradoxical protective effect of malnutrition in acetaminophen-induced liver injury.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Teresa ArrigoTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Salvatore LeonardiTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Caterina CuppariTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Sara MantiTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Angela LanzafameTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Gabriella D'AngeloTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Eloisa GittoTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Lucia MarsegliaTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
Carmelo SalpietroTeresa Arrigo, Caterina Cuppari, Sara Manti, Gabriella D'Angelo, Eloisa Gitto, Lucia Marseglia, Carmelo Salpietro, Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, 98122 Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is caused by an imbalance between the production of reactive oxygen (free radicals) and the body's ability (antioxidant capacity) to readily detoxify the reactive intermediates or easily repair the resulting damage. An adequate diet, characterized by daily intake of foods associated with improvements in the total antioxidant capacity of individuals and reduced incidence of diseases related to oxidation, can modulate the degree of oxidative stress. In fact, diet-derived micronutrients may be direct antioxidants, or are components of antioxidant enzymes, leading to improvement of some indicators of hepatic function. However, although their increased dietary intake might be beneficial, literature data are still controversial. This review summarizes what is known about the effects of diet nutrients on oxidative stress, inflammation and liver function. Moreover, we have analyzed: (1) the main nutritional components involved in the production and/or removal of free radicals; and (2) the role of free radicals in the pathogenesis of several hepatic diseases and related comorbidities.

Indexed as

Oxidative StressAnimalsAntioxidantsDietHumansInflammation MediatorsLiverLiver DiseasesNutritional StatusParenteral Nutrition, TotalReactive Oxygen SpeciesRisk FactorsTreatment OutcomeAntioxidantsInflammation MediatorsReactive Oxygen SpeciesLiver diseaseMacronutrientsMicronutrientsNutritionOxidative stress

Identifiers

PMID25593454
PMCPMC4292270
OpenAlexW2067980537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.