Evidence map›Paper›PMID 25593398›Full record

ReviewAncient science of life

The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior.

Sudipta Kumar Rath, Asit Kumar Panja, Lalit Nagar, Ashashri Shinde

Abstract readReview
In one paragraph

Review in Ancient science of life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Extraoral Taste Receptor Discovery: New Light on Ayurvedic Pharmacology.Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
  3. Review
  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sudipta Kumar RathDepartment of Dravyaguna, National Institute of Āyurveda , Jaipur, Rajasthan, India.
Asit Kumar PanjaDepartment of Basic Principles, National Institute of Āyurveda , Jaipur, Rajasthan, India.
Lalit NagarDepartment of Dravyaguna, National Institute of Āyurveda , Jaipur, Rajasthan, India.
Ashashri ShindeDepartment of Dravyaguna, National Institute of Āyurveda , Jaipur, Rajasthan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA rational and well-developed pharmacological basis forms the foundation of therapeutics in Ayurveda. The principles and theories of Ayurveda need to be validated in the scientific context in order to harness the millennia old knowledge. Rasa (taste) of the substance is the foremost tool in Ayurveda to assess and determine the pharmacological properties and actions of the substance. Similarity in rasa is said to signify similar structure and consequently similar pharmacological behavior. Depending on skills developed over the course of long-term clinical experience one, can register the minute variations in rasa of substances and accordingly the possible variations in pharmacological actions. Thus, rasa can be used as a scientific tool in the drug discovery process to limit and focus the target areas.

aimTo sensitize scientific community to the utility of rasa as a tool in the process of drug discovery. MATERIALS AND

methodsAll relevant ancient and contemporary literature was reviewed critically to form a scientific basis of the Ayurvedic concept of rasa as a tool to identify the pharmacological behavior of a substance.

conclusionThe review finds that rasa (taste) can be used as a guide to identify potential targets in drug discovery.

Indexed as

Ayurvedadrug discoverymahābhūtarasataste

Identifiers

PMID25593398
PMCPMC4293745

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.