Evidence map›Paper›PMID 25593376›Full record

ArticleIntelligence2015

Thinking positively: The genetics of high intelligence.

Nicholas G Shakeshaft, Maciej Trzaskowski, Andrew McMillan, Eva Krapohl, Michael A Simpson, Avi Reichenberg, Martin Cederlöf, Henrik Larsson, Paul Lichtenstein, Robert Plomin

Open access · hybridAbstract read
In one paragraph

Article in Intelligence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Klerman's "credo" reconsidered: neo-Kraepelinianism, Spitzer's views, and what we can learn from the past.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Nicholas G ShakeshaftKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, SE5 8AF, United Kingdom.
Maciej TrzaskowskiKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, SE5 8AF, United Kingdom.
Andrew McMillanKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, SE5 8AF, United Kingdom.
Eva KrapohlKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, SE5 8AF, United Kingdom.
Michael A SimpsonKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, SE5 8AF, United Kingdom.
Avi ReichenbergKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, SE5 8AF, United Kingdom ; Department of Psychiatry, Mount Sinai School of Medicine, NY, 10029, USA.
Martin CederlöfDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 17177 Stockholm, Sweden.
Henrik LarssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 17177 Stockholm, Sweden.
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 17177 Stockholm, Sweden.
Robert PlominKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, SE5 8AF, United Kingdom.
King's College London · GBKarolinska Institutet · SEIcahn School of Medicine at Mount Sinai · US

Funding

Genetics, School environments and cognitive developmentR01HD044454 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2005 to 2014
$3.4M
Genetics of Mathematical Cognition and DisabilitiesR01HD059215 · NICHD · OHIO STATE UNIVERSITY · PI PETRILL, STEPHEN A. · 2009 to 2012
$2.4M
European Research Council 295366Medical Research Council G0500079Medical Research Council G0901245Medical Research Council G19/2Medical Research Council G9817803NICHD NIH HHS R01 HD044454NICHD NIH HHS R01 HD059215
6 · The paper itself

Abstract

High intelligence (general cognitive ability) is fundamental to the human capital that drives societies in the information age. Understanding the origins of this intellectual capital is important for government policy, for neuroscience, and for genetics. For genetics, a key question is whether the genetic causes of high intelligence are qualitatively or quantitatively different from the normal distribution of intelligence. We report results from a sibling and twin study of high intelligence and its links with the normal distribution. We identified 360,000 sibling pairs and 9000 twin pairs from 3 million 18-year-old males with cognitive assessments administered as part of conscription to military service in Sweden between 1968 and 2010. We found that high intelligence is familial, heritable, and caused by the same genetic and environmental factors responsible for the normal distribution of intelligence. High intelligence is a good candidate for "positive genetics" - going beyond the negative effects of DNA sequence variation on disease and disorders to consider the positive end of the distribution of genetic effects.

Indexed as

Human geneticsIntelligencePositive geneticsSiblingsTwins

Identifiers

PMID25593376
PMCPMC4286575
OpenAlexW2009169403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.