ArticleIndian journal of orthopaedics
Management of skeletal metastases: An orthopaedic surgeon's guide.
Article in Indian journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Comparative study of gait parameters of patients undergoing distal femoral resections with non-operated and healthy limbs: a meta-analysis study.Frontiers in oncology · 2023Pooled it
- Surgical management of tibial metastases: a systematic review.Acta bio-medica : Atenei Parmensis · 2022Pooled it
- SEOM Clinical Guideline for bone metastases from solid tumours (2016).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2016Guideline
- ALGORITHM FOR EARLY AMBULATION IN INDIVIDUALS UNDERGOING NON-CONVENTIONAL HIP ENDOPROSTHESIS.Acta ortopedica brasileira · 2025Article
- Pilot study on the in-vitro effect of radiation therapy on bending stiffness of intramedullary photodynamic implants.Journal of orthopaedic surgery and research · 2024Article
- Physical therapist management and coordination of care to prevent pathological hip fracture from metastatic disease: a case report.Frontiers in rehabilitation sciences · 2024Article
- Effect of Bone Metastasis Cancer Board on Spinal Surgery Outcomes: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2023Review
- Article
- Operative challenges of intramedullary nailing for subtrochanteric blastic pathological femur fracture: a case report.Journal of surgical case reports · 2023Article
- Article
- Mirels' score for upper limb metastatic lesions: do we need a different cutoff for recommending prophylactic fixation?JSES international · 2022Article
- Jig-assisted modified Harrington reconstruction for metastatic bone destruction of the acetabulum.International orthopaedics · 2022Article
- Rare Case of Gaucher's Disease Presenting as a Solitary Swelling of the Proximal Tibia Mimicking a Musculoskeletal Tumor in an Adult: A Case Report.Journal of orthopaedic case reports · 2022Article
- Missed pathological femoral neck fracture undergoes spontaneous healing.Radiology case reports · 2022Article
- Communication in surgical decision-making while managing metastatic bone disease: matching patient expectations with surgical goals.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Combinatorial effect of radium-223 and irreversible electroporation on prostate cancer bone metastasis in mice.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2021Article
- DOTA-ZOL: A Promising Tool in Diagnosis and Palliative Therapy of Bone Metastasis-Challenges and Critical Points in Implementation into Clinical Routine.Molecules (Basel, Switzerland) · 2020Article
- Prediction of pathological fracture in patients with metastatic disease of the lower limb.Scientific reports · 2019Article
- Investigation of thermally induced damage to surrounding nerve tissue when using curettage and cementation of long bone tumours, modelled in cadaveric porcine femurs.Archives of orthopaedic and trauma surgery · 2019Article
- Imaging of urgencies and emergencies in the lung cancer patient.Insights into imaging · 2018Review
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2 authors.
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Abstract
Skeletal metastasis is a common cause of severe morbidity, reduction in quality of life (QOL) and often early mortality. Its prevalence is rising due to a higher rate of diagnosis, better systemic treatment, longer lives with the disease and higher disease burden rate. As people with cancer live longer and with rising sensitivity of body imaging and surveillance, the incidence of pathological fracture, metastatic epidural cord compression is rising and constitutes a challenge for the orthopedic surgeon to maintain their QOL. Metastatic disease is no longer a death sentence condemning patients to "terminal care." In the era of multidisciplinary care and effective systemic targeted and nontargeted therapy, patient expectations of QOL, even during palliative end of care period is high. We lay emphasis on proving the diagnosis of metastasis by biopsy and histopathology and discuss imaging modalities to help estimate fracture risk and map disease extent. This article discusses at length the evidence and decision-making process of various modalities to treat skeletal metastasis. The modalities range from radiation including image-guided, stereotactic and whole body radiation, systemic targeted or hormonal therapy, spinal decompression with or without stabilization, extended curettage with stabilization, resection in select cases with megaprosthetic or biological reconstruction, percutaneous procedures using radio frequency ablation, cementoplasties and discusses the role of emerging modalities like high frequency ultrasound-guided ablation, cryotherapy and whole body radionuclide therapy. The focus lies on the role of multidisciplinary care, which considers complex decisions on patient centric prognosis, comorbidities, cost, feasibility and expectations in order to maximize outcomes on QOL issues.
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