Evidence map›Paper›PMID 25593203›Full record

ReviewAJNR. American journal of neuroradiology2015

Reversible Cerebral Vasoconstriction Syndrome, Part 1: Epidemiology, Pathogenesis, and Clinical Course.

T R Miller, R Shivashankar, M Mossa-Basha, D Gandhi

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 86 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02756416 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome

TypeinterventionalSponsorUniversity of NottinghamRan2016 to 2017Enrolled10ConditionsReversible Cerebral Vasoconstriction SyndromeArmsMRI brain, ASL-MRI brain, MRA brain
NCT03509701 unknown statusnot on this mapstarted 2018, after this paper: background citation

Association Between Reversible Cerebral Vasoconstriction Syndrome and Herpes Zoster Infection

TypeobservationalSponsorAsan Medical CenterRan2018 to 2020Enrolled40ConditionsReversible Cerebral Vasoconstriction Syndrome, Varicella-zoster Virus InfectionArmsVZV-specific antibody response from blood
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 226 citations in OpenAlex.

  1. Spinal cord involvement in primary central nervous system vasculitis. A systematic review of clinical, neuroradiological and pathological findings.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  8. Reversible cerebral vasoconstriction syndrome and bilateral Eagle Syndrome cause recurrent reversible carotid artery stenosis and cerebral infarction.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

T R MillerFrom the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland.
R ShivashankarFrom the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland.
M Mossa-BashaDepartment of Diagnostic Radiology (M.M.-B.), Section of Neuroradiology, University of Washington, Seattle, Washington.
D GandhiFrom the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland Dgandhi@umm.edu.
University of Maryland Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reversible cerebral vasoconstriction syndrome is a clinical and radiologic syndrome that represents a common presentation of a diverse group of disorders. The syndrome is characterized by thunderclap headache and reversible vasoconstriction of cerebral arteries, which can either be spontaneous or related to an exogenous trigger. The pathophysiology of reversible cerebral vasoconstriction syndrome is unknown, though alterations in cerebral vascular tone are thought to be a key underlying mechanism. The syndrome typically follows a benign course; however, reversible cerebral vasoconstriction syndrome may result in permanent disability or death in a small minority of patients secondary to complications such as ischemic stroke or intracranial hemorrhage.

Indexed as

VasoconstrictionAdultBrainCerebral Arterial DiseasesCerebral ArteriesFemaleHeadache Disorders, PrimaryHumansIntracranial HemorrhagesPrognosisStrokeSyndromeVasospasm, Intracranial

Identifiers

PMID25593203
PMCPMC7964694
OpenAlexW2126541326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.