Evidence map›Paper›PMID 25592444›Full record

Observational studyBMC cardiovascular disorders2015

Management and outcomes of acute ST-segment-elevation myocardial infarction at a tertiary-care hospital in Sri Lanka: an observational study.

Ruwanthi Bandara, Arjuna Medagama, Ruwan Munasinghe, Nandana Dinamithra, Amila Subasinghe, Jayantha Herath, Mahesh Ratnayake, Buddhini Imbulpitiya, Ameena Sulaiman

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Acute coronary syndrome treatment delay in low to middle-income countries: A systematic review.International journal of cardiology. Heart & vasculature · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ruwanthi Bandara
Arjuna MedagamaDepartment of Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka. arjuna.medagama@gmail.com.
Ruwan Munasinghe
Nandana Dinamithra
Amila Subasinghe
Jayantha Herath
Mahesh Ratnayake
Buddhini Imbulpitiya
Ameena Sulaiman
University of Peradeniya · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSri Lanka is a developing country with a high rate of cardiovascular mortality. It is still largely dependent on thrombolysis for primary management of acute myocardial infarction. The aim of this study was to present current data on the presentation, management, and outcomes of acute ST-segment-elevation myocardial infarction (STEMI) at a tertiary-care hospital in Sri Lanka.

methodsEighty-one patients with acute STEMI presenting to a teaching hospital in Peradeniya, Sri Lanka, were included in this observational study.

resultsMedian interval between symptom onset and hospital presentation was 60 min (mean 212 min). Thrombolysis was performed in 73% of patients. The most common single reason for not performing thrombolysis was delayed presentation. Median door-to-needle time was 64 min (mean, 98 min). Only 16.9% of patients received thrombolysis within 30 min, and none underwent primary PCI. Over 98% of patients received aspirin, clopidogrel, and a statin on admission. Intravenous and oral beta blockers were rarely used. Follow-up data were available for 93.8% of patients at 1 year. One-year mortality rate was 12.3%. Coronary intervention was performed in only 7.3% of patients post infarction.

conclusionLate presentation to hospital remains a critical factor in thrombolysis of STEMI patients in Sri Lanka. Thrombolysis was not performed within 30 min of admission in the majority of patients. First-contact physicians should receive further training on effective thrombolysis, and there is an urgent need to explore the ways in which PCI and post-infarction interventions can be incorporated into treatment protocols.

Indexed as

Thrombolytic TherapyAgedAngioplasty, Balloon, CoronaryDrug Therapy, CombinationElectrocardiographyFemaleFibrinolytic AgentsHospitalizationHospitals, TeachingHumansMaleMiddle AgedMyocardial InfarctionProspective StudiesRisk FactorsSri LankaFibrinolytic AgentsStreptokinase

Identifiers

PMID25592444
PMCPMC4361140
OpenAlexW1567691403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.