Evidence map›Paper›PMID 25591816›Full record

ArticleAnnals of clinical microbiology and antimicrobials2015

Epidemiology of CTX-M-type extended-spectrum beta-lactamase (ESBL)-producing nosocomial -Escherichia coli infection in China.

Huiqing Shi, Fengjun Sun, Jianhong Chen, Qianyi Ou, Wei Feng, Xiaolan Yong, Peiyuan Xia

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Observational
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  7. Article
  8. Occurrence and Antimicrobial Resistance Traits ofInternational journal of environmental research and public health · 2020
    Article
  9. Extended-spectrum β-lactamase-producingJournal of equine science · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Huiqing ShiDepartment of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China. huiqingshi@163.com.
Fengjun SunDepartment of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China. fengj_sun@163.com.
Jianhong ChenDepartment of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China. jhchen_chen@163.com.
Qianyi OuDepartment of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China. qianyiou_ou@126.com.
Wei FengDepartment of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China. fengwei.sky@163.com.
Xiaolan YongDepartment of Clinical Pharmacy, General Hospital of Chengdu Military Region, Chengdu, Sichuan Province, 610083, China. xiaolan_yong@126.com.
Peiyuan XiaDepartment of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China. peiyuan_xia2013@163.com.
Army Medical University · CNSouthwest Hospital · CNChengdu Military General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEscherichia coli is one of the most common clinical pathogens causing nosocomial infection. The widespread cefotaxime-beta lactamases (CTX) has increased the multidrug resistance (MDR) of E. coli and has brought great trouble to the doctor treating the infection.

methodsESBL-positive E. coli isolates were collected from different hospitals in different areas and the minimal inhibitory concentration (MIC) was analyzed by the agar dilution method. The resistance gene types were detected using polymerase chain reaction (PCR) and the sequence types were determined by multilocus sequence typing (MLST).

resultsWe found that the blaCTX-M-1 group and the blaCTX-M-9 group were the main CTX-M gene types, with many kinds of MLST gene types. Except for TEM with high isolate, SHV, OXA and VEB were relatively rare, while no PER and GES was detected. Most strains may have other resistance mechanisms, and the ESBL positive strains have high resistance not only to cephalosporins but also to other kinds of antibiotics.

conclusionThe study provides wide epidemiological data and enables more effective infection control and treatment plans.

Indexed as

Anti-Bacterial Agentsbeta-LactamasesChinaCross InfectionDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsHospitalsHumansMicrobial Sensitivity TestsMultilocus Sequence TypingAnti-Bacterial Agentsbeta-Lactamases

Identifiers

PMID25591816
PMCPMC4299296
OpenAlexW2157721101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.