ArticleScientific reports2015
Biomimetic synthesis of struvite with biogenic morphology and implication for pathological biomineralization.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 80 citations in OpenAlex.
- Organic Molecules are Involved in Ni-Struvite Biomineralization by Streptomyces mirabilis.Molecular biotechnology · 2026Article
- Nutrient Separation Systems: Current Progress and Future Opportunities.ACS ES&T engineering · 2026Review
- Microbial factors behind struvite precipitation: enzymes and extracellular polymeric substances (EPS) as key players.Applied microbiology and biotechnology · 2025Article
- TargetingFrontiers in cellular and infection microbiology · 2025Article
- Understanding the role of zinc ions on struvite nucleation and growth in the context of infection urinary stones.Metallomics : integrated biometal science · 2024Article
- Substances Secreted byInternational journal of molecular sciences · 2023Article
- Scalable Production of Peptides for Enhanced Struvite Formation via Expression on the Surface of Genetically Engineered Microbes.ACS materials Au · 2023Article
- A magnetic hydrogel for the efficient retrieval of kidney stone fragments during ureteroscopy.Nature communications · 2023Article
- Consumption of soft drinks rich in phosphoric acid versus struvite crystallization from artificial urine.Scientific reports · 2022Article
- Biomineralization of Nickel Struvite Linked to Metal Resistance inMolecules (Basel, Switzerland) · 2022Article
- Influence of Phosphorus Sources on the Compressive Strength and Microstructure of Ferronickel Slag-Based Magnesium Phosphate Cement.Materials (Basel, Switzerland) · 2022Article
- 1H NMR metabolic profiling of Staphylococcus pseudintermedius isolated from canine uroliths.PloS one · 2022Article
- Exploring the effect of a peptide additive on struvite formation and morphology: a high-throughput method.RSC advances · 2020Article
- Shape and structure controlling of calcium oxalate crystals by a combination of additives in the process of biomineralization.RSC advances · 2018Article
- Article
- Rationally designed mineralization for selective recovery of the rare earth elements.Nature communications · 2017Article
- Enhanced MFC power production and struvite recovery by the addition of sea salts to urine.Water research · 2017Article
- Phosphate enhance recovery from wastewater by mechanism analysis and optimization of struvite settleability in fluidized bed reactor.Scientific reports · 2016Article
- Vitamin C inhibits crystallization of struvite from artificial urine in the presence of Pseudomonas aeruginosa.International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have found that certain urinary proteins can efficiently inhibit stone formation. These discoveries are significant for developing effective therapies for stone disease, but the inhibition mechanism of crystallization remains elusive. In the present study, polyaspartic acid (PASP) was employed as a model peptide to investigate the effect of urinary proteins on the crystallization and morphological evolution of struvite. The results demonstrate that selective adsorption/binding of PASP onto the {010} and {101} faces of struvite crystals results in arrowhead-shaped morphology, which further evolves into X-shaped and unusual tabular structures with time. Noticeably, these morphologies are reminiscent of biogenic struvite morphology. Concentration-dependent experiments show that PASP can inhibit struvite growth and the inhibitory capacity increases with increasing PASP concentration, whereas aspartic acid monomers do not show a significant effect. Considering that PASP is a structural and functional analogue of the subdomains of aspartic acid-rich proteins, our results reveal that aspartic acid-rich proteins play a key role in regulating biogenic struvite morphology, and aspartic acid residues contribute to the inhibitory capacity of urinary proteins. The potential implications of PASP for developing therapeutic agents for urinary stone disease is also discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.