ReviewACS chemical biology2015
Defining the orphan functions of lysine acetyltransferases.
Review in ACS chemical biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 44 citations in OpenAlex.
- Photoredox-Catalyzed Lysine C(spJournal of the American Chemical Society · 2026Article
- Antemortem Stress Regulates Postmortem Glycolysis in Muscle by Deacetylation of Pyruvate Kinase M1 at K141.The protein journal · 2024Article
- A global view of the human post-translational modification landscape.The Biochemical journal · 2023Review
- Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease.Genes · 2023Review
- Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.ACS medicinal chemistry letters · 2021Article
- How Elongator Acetylates tRNA Bases.International journal of molecular sciences · 2020Review
- Chromatin dynamics and histone modifications in intestinal microbiota-host crosstalk.Molecular metabolism · 2020Review
- Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation.Molecular systems biology · 2020Article
- Epigenetic regulation by endogenous metabolite pharmacology.Current opinion in chemical biology · 2019Review
- Review
- DNA polymerase ι is acetylated in response to SScientific reports · 2019Article
- Bioorthogonal pro-metabolites for profiling short chain fatty acylation.Chemical science · 2018Article
- The Complete Genome and Physiological Analysis of the Eurythermal FirmicuteFrontiers in microbiology · 2018Article
- Yersinia pestis acetyltransferase-mediated dual acetylation at the serine and lysine residues enhances the auto-ubiquitination of ubiquitin ligase MARCH8 in human cells.Cell cycle (Georgetown, Tex.) · 2017Article
- Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.Cell chemical biology · 2017Article
- Epigenetic assays for chemical biology and drug discovery.Clinical epigenetics · 2017Review
- Global Profiling of Acetyltransferase Feedback Regulation.Journal of the American Chemical Society · 2016Article
- Microfluidic Mobility Shift Profiling of Lysine Acetyltransferases Enables Screening and Mechanistic Analysis of Cellular Acetylation Inhibitors.ACS chemical biology · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Long known for their role in histone acetylation, recent studies have demonstrated that lysine acetyltransferases also carry out distinct "orphan" functions. These activities impact a wide range of biological phenomena including metabolism, RNA modification, nuclear morphology, and mitochondrial function. Here, we review the discovery and characterization of orphan lysine acetyltransferase functions. In addition to highlighting the evidence and biological role for these functions in human disease, we discuss the part emerging chemical tools may play in investigating this versatile enzyme superfamily.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.