Evidence map›Paper›PMID 25591023›Full record

ArticleJournal of applied oral science : revista FOB

Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles.

Leticia Boldrin Mestieri, Mário Tanomaru-Filho, Ana Livia Gomes-Cornélio, Loise Pedrosa Salles, Maria Inês Basso Bernardi, Juliane Maria Guerreiro-Tanomaru

Abstract read
In one paragraph

Article in Journal of applied oral science : revista FOB. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leticia Boldrin MestieriDepartment of Restorative Dentistry, Araraquara Dental School, Univ. Estadual Paulista, Araraquara, SP, Brazil.
Mário Tanomaru-FilhoDepartment of Restorative Dentistry, Araraquara Dental School, Univ. Estadual Paulista, Araraquara, SP, Brazil.
Ana Livia Gomes-CornélioDepartment of Restorative Dentistry, Araraquara Dental School, Univ. Estadual Paulista, Araraquara, SP, Brazil.
Loise Pedrosa SallesDepartment of Restorative Dentistry, Araraquara Dental School, Univ. Estadual Paulista, Araraquara, SP, Brazil.
Maria Inês Basso BernardiInstitute of Physics, University of São Paulo, São Carlos, SP, Brazil.
Juliane Maria Guerreiro-TanomaruDepartment of Restorative Dentistry, Araraquara Dental School, Univ. Estadual Paulista, Araraquara, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: (1) PC; (2) White MTA; (3) PC+30% Nbµ; (4) PC+30% Nbη. MATERIAL AND

methodsFor the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay.

resultsThe results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA.

conclusionsIt was concluded that the combination of PC+NbO is a potential alternative for composition of MTA.

Indexed as

Aluminum CompoundsAnalysis of VarianceBiocompatible MaterialsCalcium CompoundsCells, CulturedCell SurvivalDental CementsDrug CombinationsFormazansHumansMaterials TestingNanoparticlesNiobiumOsteoblastsOxidesSilicatesAluminum CompoundsBiocompatible MaterialsCalcium CompoundsDental CementsDrug CombinationsFormazansmineral trioxide aggregateMTT formazanNiobiumOxidesSilicatesTetrazolium Salts

Identifiers

PMID25591023
PMCPMC4307770

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.