Evidence map›Paper›PMID 25590558›Full record

ReviewCell cycle (Georgetown, Tex.)2015

Meiotic crossover patterns: obligatory crossover, interference and homeostasis in a single process.

Shunxin Wang, Denise Zickler, Nancy Kleckner, Liangran Zhang

Abstract readReview
In one paragraph

Review in Cell cycle (Georgetown, Tex.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Ufd2p promotes efficient crossover formation by destabilizing Top2p during meiosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Article
  10. Mouse X-linked microRNA cluster regulates the meiotic checkpoint andProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Hurdles of Sperm Success: Exploring the Role of DNases.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shunxin Wanga Department of Molecular and Cellular Biology ; Harvard University ; Cambridge , MA USA.
Denise Zickler
Nancy Kleckner
Liangran Zhang

Funding

MEIOTIC CHROMOSOME SYNAPSIS AND RECOMBINATION IN YEASTR01GM044794 · NIGMS · HARVARD UNIVERSITY · PI KLECKNER, NANCY E · 1990 to 2018
$13.8M
NIGMS NIH HHS R01 GM044794NIGMS NIH HHS R01GM044794
6 · The paper itself

Abstract

During meiosis, crossover recombination is tightly regulated. A spatial patterning phenomenon known as interference ensures that crossovers are well-spaced along the chromosomes. Additionally, every pair of homologs acquires at least one crossover. A third feature, crossover homeostasis, buffers the system such that the number of crossovers remains steady despite decreases or increases in the number of earlier recombinational interactions. Here we summarize recent work from our laboratory supporting the idea that all 3 of these aspects are intrinsic consequences of a single basic process and suggesting that the underlying logic of this process corresponds to that embodied in a particular (beam-film) model.

Indexed as

Crossing Over, GeneticHomeostasisMeiosisChromosomesModels, Biologicalbeam-film modelBF, beam-filmCO, crossovercrossovercrossover homeostasiscrossover interferenceDDF, designation driving forceDSBs, double-strand breaksmeiosisNCO, noncrossoverobligatory crossoverrecombinationSC, synaptonemal complexSTUbL, SUMO-targeted ubiquitin ligase

Identifiers

PMID25590558
PMCPMC4353236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.