Evidence map›Paper›PMID 25590050›Full record

ArticleEvolutionary computation, machine learning and data mining in bioinformatics. EvoBIO (Conference)

Replication of

Janina M Jeff, Kristin Brown-Gentry, Robert Goodloe, Marylyn D Ritchie, Joshua C Denny, Abel N Kho, Loren L Armstrong, Bob McClellan, Ping Mayo, Melissa Allen and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evolutionary computation, machine learning and data mining in bioinformatics. EvoBIO (Conference). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Janina M JeffCharles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Kristin Brown-GentryCenter for Human Genetics Research, Vanderbilt University, Nashville, TN 37232, USA.
Robert GoodloeDepartment of Medicine, Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Marylyn D RitchieDepartment of Biomedical Informatics, Vanderbilt University, Nashville, TN 37232, USA.
Joshua C DennyDivision of General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Abel N KhoDivision of Endocrinology, Metabolism, and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Loren L ArmstrongOffice of Personalized Medicine, Vanderbilt University, Nashville, TN 37232, USA.
Bob McClellanCenter for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Ping MayoDepartment of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Melissa AllenDepartment of Biochemistry and Molecular Biology, Penn State University, University Park, PA 16802, USA.
Hailing JinUniversity of Washington Medical Center, Seattle, WA 98195, USA.
Niloufar B Gillani
Nathalie Schnetz-Boutaud
Holli H Dilks
Melissa A Basford
Jennifer A Pacheco
Gail P Jarvik
Rex L Chisholm
Dan M Roden
M Geoffrey Hayes
Dana C Crawford

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Vanderbilt/Meharry Initiative for Minority Student DvptR25GM062459 · NIGMS · VANDERBILT UNIVERSITY · PI VELEZ EDWARDS, DIGNA R · 2002 to 2020
$10.4M
Epidemiologic Architecture for Genes Linked to Environment (EAGLE)U01HG004798 · NHGRI · VANDERBILT UNIVERSITY · PI CRAWFORD, DANA C · 2008 to 2013
$8.8M
TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Vanderbilt Genome-Electronic Records ProjectU01HG004603 · NHGRI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2007 to 2011
$7.3M
Genome-wide Studies from the NUgene BiorespositoryU01HG004609 · NHGRI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHISHOLM, REX L · 2007 to 2010
$3.7M
Training Program on Genetic Variation and Human PhenotypesT32GM080178 · NIGMS · VANDERBILT UNIVERSITY · PI COX, NANCY J, SAMUELS, DAVID C · 2007 to 2021
$3.1M
NCATS NIH HHS UL1 TR000445NHGRI NIH HHS U01 HG004603NHGRI NIH HHS U01 HG004609NHGRI NIH HHS U01 HG004798NHLBI NIH HHS T32 HL007824NIGMS NIH HHS R25 GM062459NIGMS NIH HHS T32 GM080178
6 · The paper itself

Abstract

The NAv1.5 sodium channel α subunit is the predominant α-subunit expressed in the heart and is associated with cardiac arrhythmias. We tested five previously identified

Indexed as

African Americanselectrocardiographic traitselectronic medical recordseMERGEepidemiologygenetic association studyNHANES

Identifiers

PMID25590050
PMCPMC4290789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.